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A CRISPR-Cas9–integrase complex generates precise DNA fragments for genome integration
Shrutee Jakhanwal, Brady F Cress, Pascal Maguin, Marco J Lobba, Luciano A Marraffini, Jennifer A Doudna
Publication Date: 08 March, 2021
Article Pages: 10 Open access contents
Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter
Moïra B Dion, Pier-Luc Plante, Edwige Zufferey, Shiraz A Shah, Jacques Corbeil, Sylvain Moineau
Publication Date: 02 March, 2021
Article Pages: 11 Open access contents
A benchmark and an algorithm for detecting germline transposon insertions and measuring <i>de novo</i> transposon insertion frequencies
Tianxiong Yu, Xiao Huang, Shengqian Dou, Xiaolu Tang, Shiqi Luo, William E Theurkauf, Jian Lu, Zhiping Weng
Publication Date: 28 January, 2021
Article Pages: 1 Open access contents
SurVirus: a repeat-aware virus integration caller
Ramesh Rajaby, Yi Zhou, Yifan Meng, Xi Zeng, Guoliang Li, Peng Wu, Wing-Kin Sung
Publication Date: 14 January, 2021
Article Pages: 1 Open access contents
Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients
Wei-Feng Guo, Shao-Wu Zhang, Yue-Hua Feng, Jing Liang, Tao Zeng, Luonan Chen
Publication Date: 12 January, 2021
Article Pages: 1 Open access contents
Entropy subspace separation-based clustering for noise reduction (ENCORE) of scRNA-seq data
Jia Song, Yao Liu, Xuebing Zhang, Qiuyue Wu, Juan Gao, Wei Wang, Jin Li, Yanling Song, Chaoyong Yang
Publication Date: 10 December, 2020
Article Pages: 1 Open access contents
Predicting regulatory variants using a dense epigenomic mapped CNN model elucidated the molecular basis of trait-tissue associations
Guangsheng Pei, Ruifeng Hu, Yulin Dai, Astrid Marilyn Manuel, Zhongming Zhao, Peilin Jia
Publication Date: 09 December, 2020
Article Pages: 13 Open access contents
Genome-wide integration site detection using Cas9 enriched amplification-free long-range sequencing
Joost van Haasteren, Altar M Munis, Deborah R Gill, Stephen C Hyde
Publication Date: 08 December, 2020
Article Pages: 1 Open access contents
NGS-based identification and tracing of microsatellite instability from minute amounts DNA using inter-Alu-PCR
Fangyan Yu, Ka Wai Leong, Alexander Makrigiorgos, Viktor A Adalsteinsson, Ioannis Ladas, Kimmie Ng, Harvey Mamon, G Mike Makrigiorgos
Publication Date: 08 December, 2020
Article Pages: 1 Open access contents
UniPath: a uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles
Smriti Chawla, Sudhagar Samydurai, Say Li Kong, Zhengwei Wu, Zhenxun Wang, Wai Leong TAM, Debarka Sengupta, Vibhor Kumar
Publication Date: 04 December, 2020
Article Pages: 1 Open access contents