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Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats
Haiyan Fan, Rui Ding, Wenchao Liu, Xin zhang, Ran Li, Boyang Wei, Shixing Su, Fa Jin, Chengcong Wei, Xuying He, Xifeng Li, Chuanzhi Duan
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Article Pages: 1 Open access contents
OGG1 co-inhibition antagonizes the tumor-inhibitory effects of targeting MTH1
Ling Zhang, Laura Misiara, Govindi J. Samaranayake, Nisha Sharma, Dao M. Nguyen, Yu-Ki Tahara, Eric T. Kool, Priyamvada Rai
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Article Pages: 1 Open access contents
Hypochlorite-induced aggregation of fibrinogen underlies a novel antioxidant role in blood plasma
Noralyn Mañucat-Tan, Rafaa Zeineddine Abdallah, Harsimran Kaur, Daniel Saviane, Mark R. Wilson, Amy R. Wyatt
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Article Pages: 1 Open access contents
The program of renal fibrogenesis is controlled by microRNAs regulating oxidative metabolism
Verónica Miguel, Ricardo Ramos, Laura García-Bermejo, Diego Rodríguez-Puyol, Santiago Lamas
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Article Pages: 1 Open access contents
Trem2 mediated Syk-dependent ROS amplification is essential for osteoclastogenesis in periodontitis microenvironment
Yuteng Weng, Haicheng Wang, Lin Li, Yanhuizhi Feng, Shuyu Xu, Zuolin Wang
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Article Pages: 1 Open access contents
Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models
Ifat Alsharif, Loubna Boukhzar, Benjamin Lefranc, David Godefroy, Juliette Aury-Landas, Jean-Luc do Rego, Jean-Claude do Rego, Frédéric Naudet, Arnaud Arabo, Abdeslam Chagraoui, David Maltête, Abdelhamid Benazzouz, Catherine Baugé, Jérôme Leprince, Abdel G. Elkahloun, Lee E. Eiden, Youssef Anouar
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Article Pages: 1 Open access contents
RhoA GTPase phosphorylated at tyrosine 42 by src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A
Jae-Gyu Kim, Shohel Mahmud, Jung Ki Min, Yoon-Beom Lee, Hyunbin Kim, Dong-Chul Kang, Hwee-Seon Park, Jihye Seong, Jae-Bong Park
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Article Pages: 1 Open access contents
HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress
Annadurai Thangaraj, Ernest T. Chivero, Ashutosh Tripathi, Seema Singh, Fang Niu, Ming-Lei Guo, Prakash Pillai, Palsamy Periyasamy, Shilpa Buch
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Article Pages: 1 Open access contents
NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice
M. Herranz-Itúrbide, J. López-Luque, E. Gonzalez-Sanchez, D. Caballero-Díaz, E. Crosas-Molist, B. Martín-Mur, M. Gut, A. Esteve-Codina, V. Jaquet, J.X. Jiang, N.J. Török, I. Fabregat
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Article Pages: 1 Open access contents
Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation
Yi Hui Yee, Stephen Jun Fei Chong, Li Ren Kong, Boon Cher Goh, Shazib Pervaiz
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Article Pages: 1 Open access contents