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Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria
Rubén Quintana-Cabrera, Israel Manjarrés-Raza, Carlos Vicente-Gutiérrez, Mauro Corrado, Juan P. Bolaños, Luca Scorrano
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Article Pages: 1 Open access contents
<i>Htd2</i> deficiency-associated suppression of α-lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes
Mengqi Zeng, Jie Xu, Zhengyi Zhang, Xuan Zou, Xueqiang Wang, Ke Cao, Weiqiang Lv, Yuting Cui, Jiangang Long, Zhihui Feng, Jiankang Liu
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Article Pages: 1 Open access contents
NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases
Min Woo Park, Hyeon Woo Cha, Junhyung Kim, Jung Han Kim, Haesung Yang, Sunmi Yoon, Napissara Boonpraman, Sun Shin Yi, Ik Dong Yoo, Jong-Seok Moon
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Article Pages: 1 Open access contents
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation
Jialei Sun, Chenhao Zhou, Yue Zhao, Xiaofei Zhang, Wanyong Chen, Qiang Zhou, Bo Hu, Dongmei Gao, Lisa Raatz, Zhefang Wang, Peter J. Nelson, Yuchao Jiang, Ning Ren, Christiane J. Bruns, Haijun Zhou
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Article Pages: 1 Open access contents
Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21
Bo Ren, Luanfeng Wang, Lin Shi, Xin Jin, Yan Liu, Rui Hai Liu, Fei Yin, Enrique Cadenas, Xiaoshuang Dai, Zhigang Liu, Xuebo Liu
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Article Pages: 1 Open access contents
Therapeutic wavelengths of ultraviolet B radiation activate apoptotic, circadian rhythm, redox signalling and key canonical pathways in psoriatic epidermis
Rachel Addison, Sophie C. Weatherhead, Anandika Pawitri, Graham R. Smith, Ashley Rider, Henry J. Grantham, Simon J. Cockell, Nick J. Reynolds
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Article Pages: 1 Open access contents
Progression from Monoclonal gammopathy of undetermined significance of the immunoglobulin M class (IgM-MGUS) to Waldenstrom Macroglobulinemia is associated with an alteration in lipid metabolism
Shahrzad Jalali, Jie Shi, Nagib Ahsan, LindaE. Wellik, MaKayla Serres, Alex Buko, Jonas Paludo, HyoJin Kim, XinYi Tang, Zhi-Zhang Yang, AnneJ. Novak, RobertA. Kyle, StephenM. Ansell
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Article Pages: 1 Open access contents
mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264.7 mouse monocytes
Qin Luo, Yuzhen Son, Jingjing Kang, Yuchen Wu, Fengsun Wu, Yueqin Li, Qing Dong, Jun Wang, Chao Song, Hongrui Guo
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Article Pages: 1 Open access contents
Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium
Kohei Homma, Eriko Toda, Hideto Osada, Norihiro Nagai, Takumi Era, Kazuo Tsubota, Hideyuki Okano, Yoko Ozawa
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Article Pages: 1 Open access contents
Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis
Yuanyuan Guo, Xiong Jia, Yongzhi Cui, Yu Song, Siyuan Wang, Yongtao Geng, Rui Li, Weihang Gao, Dehao Fu
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Article Pages: 1 Open access contents