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A programmable omnipotent Argonaute nuclease from mesophilic bacteria <i>Kurthia massiliensis</i>
Yang Liu, Wenqiang Li, Xiaoman Jiang, Yaping Wang, Zhiwei Zhang, Qi Liu, Ruyi He, Quan Chen, Jun Yang, Longyu Wang, Fei Wang, Lixin Ma
Publication Date: 14 January, 2021
Article Pages: 11 Open access contents
Pentapeptide repeat protein QnrB1 requires ATP hydrolysis to rejuvenate poisoned gyrase complexes
Łukasz Mazurek, Dmitry Ghilarov, Elizabeth Michalczyk, Zuzanna Pakosz, Mikhail Metelev, Wojciech Czyszczoń, Karolina Wawro, Iraj Behroz, Svetlana Dubiley, Roderich D Süssmuth, Jonathan G Heddle
Publication Date: 12 January, 2021
Article Pages: 15 Open access contents
Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering
Kassidy J Tompkins, Mo Houtti, Lauren A Litzau, Eric J Aird, Blake A Everett, Andrew T Nelson, Leland Pornschloegl, Lidia K Limón-Swanson, Robert L Evans, Karen Evans, Ke Shi, Hideki Aihara, Wendy R Gordon
Publication Date: 07 January, 2021
Article Pages: 18 Open access contents
Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses
Jieyu Yang, Xuping Jing, Wenfu Yi, Xiao-Dan Li, Chen Yao, Bo Zhang, Zhenhua Zheng, Hanzhong Wang, Peng Gong
Publication Date: 06 January, 2021
Article Pages: 13 Open access contents
Terminal deoxynucleotidyl transferase-mediated formation of protein binding polynucleotides
Jon Ashley, Anna-Lisa Schaap-Johansen, Mohsen Mohammadniaei, Maryam Naseri, Paolo Marcatili, Marta Prado, Yi Sun
Publication Date: 04 January, 2021
Article Pages: 9 Open access contents
Determinants of adenine-mutagenesis in diversity-generating retroelements
Sumit Handa, Andres Reyna, Timothy Wiryaman, Partho Ghosh
Publication Date: 24 December, 2020
Article Pages: 12 Open access contents
<i>Pseudomonas putida</i> MPE, a manganese-dependent endonuclease of the binuclear metallophosphoesterase superfamily, incises single-strand DNA in two orientations to yield a mixture of 3′-PO<sub>4</sub> and 3′-OH termini
Shreya Ghosh, Anam Ejaz, Lucas Repeta, Stewart Shuman
Publication Date: 24 December, 2020
Article Pages: 9 Open access contents
Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6
Tommaso Selmi, Shobbir Hussain, Sabine Dietmann, Matthias Heiß, Kayla Borland, Sophia Flad, Jean-Michel Carter, Rebecca Dennison, Ya-Lin Huang, Stefanie Kellner, Susanne Bornelöv, Michaela Frye
Publication Date: 16 December, 2020
Article Pages: 16 Open access contents
G-Quadruplex loops regulate PARP-1 enzymatic activation
Andrea D Edwards, John C Marecki, Alicia K Byrd, Jun Gao, Kevin D Raney
Publication Date: 11 December, 2020
Article Pages: 15 Open access contents