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<i>In vivo</i> phage display: identification of organ-specific peptides using deep sequencing and differential profiling across tissues
Karlis Pleiko, Kristina Põšnograjeva, Maarja Haugas, Päärn Paiste, Allan Tobi, Kaarel Kurm, Una Riekstina, Tambet Teesalu
Publication Date: 14 January, 2021
Article Pages: 1 Open access contents
The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation
Zongling Ji, Yaoyong Li, Sean X Liu, Andrew D Sharrocks
Publication Date: 12 January, 2021
Article Pages: 18 Open access contents
Pentapeptide repeat protein QnrB1 requires ATP hydrolysis to rejuvenate poisoned gyrase complexes
Łukasz Mazurek, Dmitry Ghilarov, Elizabeth Michalczyk, Zuzanna Pakosz, Mikhail Metelev, Wojciech Czyszczoń, Karolina Wawro, Iraj Behroz, Svetlana Dubiley, Roderich D Süssmuth, Jonathan G Heddle
Publication Date: 12 January, 2021
Article Pages: 15 Open access contents
Multiprotein <i>E. coli</i> SSB–ssDNA complex shows both stable binding and rapid dissociation due to interprotein interactions
M Nabuan Naufer, Michael Morse, Guðfríður Björg Möller, James McIsaac, Ioulia Rouzina, Penny J Beuning, Mark C Williams
Publication Date: 12 January, 2021
Article Pages: 17 Open access contents
Insights into synthesis and function of KsgA/Dim1-dependent rRNA modifications in archaea
Robert Knüppel, Christian Trahan, Michael Kern, Alexander Wagner, Felix Grünberger, Winfried Hausner, Tessa E F Quax, Sonja-Verena Albers, Marlene Oeffinger, Sébastien Ferreira-Cerca
Publication Date: 12 January, 2021
Article Pages: 25 Open access contents
Comparison of loop extrusion and diffusion capture as mitotic chromosome formation pathways in fission yeast
Tereza Gerguri, Xiao Fu, Yasutaka Kakui, Bhavin S Khatri, Christopher Barrington, Paul A Bates, Frank Uhlmann
Publication Date: 12 January, 2021
Article Pages: 18 Open access contents
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development
Yalan Yang, Xinhao Fan, Junyu Yan, Muya Chen, Min Zhu, Yijie Tang, Siyuan Liu, Zhonglin Tang
Publication Date: 12 January, 2021
Article Pages: 16 Open access contents
Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients
Wei-Feng Guo, Shao-Wu Zhang, Yue-Hua Feng, Jing Liang, Tao Zeng, Luonan Chen
Publication Date: 12 January, 2021
Article Pages: 1 Open access contents
A supernumerary designer chromosome for modular <i>in vivo</i> pathway assembly in <i>Saccharomyces cerevisiae</i>
Eline D Postma, Sofia Dashko, Lars van Breemen, Shannara K Taylor Parkins, Marcel van den Broek, Jean-Marc Daran, Pascale Daran-Lapujade
Publication Date: 11 January, 2021
Article Pages: 14 Open access contents
A hotspot for enhancing insulin receptor activation revealed by a conformation-specific allosteric aptamer
Na-Oh Yunn, Mangeun Park, Seongeun Park, Jimin Lee, Jeongeun Noh, Euisu Shin, Sung Ho Ryu
Publication Date: 07 January, 2021
Article Pages: 12 Open access contents
Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering
Kassidy J Tompkins, Mo Houtti, Lauren A Litzau, Eric J Aird, Blake A Everett, Andrew T Nelson, Leland Pornschloegl, Lidia K Limón-Swanson, Robert L Evans, Karen Evans, Ke Shi, Hideki Aihara, Wendy R Gordon
Publication Date: 07 January, 2021
Article Pages: 18 Open access contents
The <i>MDM2</i> inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
Sara Lago, Matteo Nadai, Emanuela Ruggiero, Martina Tassinari, Maja Marušič, Beatrice Tosoni, Ilaria Frasson, Filippo M Cernilogar, Valentina Pirota, Filippo Doria, Janez Plavec, Gunnar Schotta, Sara N Richter
Publication Date: 07 January, 2021
Article Pages: 16 Open access contents
The fission yeast Pin1 peptidyl-prolyl isomerase promotes dissociation of Sty1 MAPK from RNA polymerase II and recruits Ssu72 phosphatase to facilitate oxidative stress induced transcription
Yi-Ting Wang, Wan-Yi Hsiao, Shao-Win Wang
Publication Date: 07 January, 2021
Article Pages: 12 Open access contents
Effects of codon usage on gene expression are promoter context dependent
Qian Yang, Xueliang Lyu, Fangzhou Zhao, Yi Liu
Publication Date: 07 January, 2021
Article Pages: 13 Open access contents
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes
Paulina Galka-Marciniak, Martyna Olga Urbanek-Trzeciak, Paulina Maria Nawrocka, Piotr Kozlowski
Publication Date: 06 January, 2021
Article Pages: 19 Open access contents
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