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TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form <i>Trypanosoma brucei</i>
Carys Davies, Cher-Pheng Ooi, Georgios Sioutas, Belinda S Hall, Haneesh Sidhu, Falk Butter, Sam Alsford, Bill Wickstead, Gloria Rudenko
Publication Date: 28 February, 2021
Article Pages: 20 Open access contents
Anti-CRISPR AcrIF9 functions by inducing the CRISPR–Cas complex to bind DNA non-specifically
Wang-Ting Lu, Chantel N Trost, Hanna Müller-Esparza, Lennart Randau, Alan R Davidson
Publication Date: 28 February, 2021
Article Pages: 12 Open access contents
Targeted-antibacterial-plasmids (TAPs) combining conjugation and CRISPR/Cas systems achieve strain-specific antibacterial activity
Audrey Reuter, Cécile Hilpert, Annick Dedieu-Berne, Sophie Lematre, Erwan Gueguen, Guillaume Launay, Sarah Bigot, Christian Lesterlin
Publication Date: 28 February, 2021
Article Pages: 14 Open access contents
A Hi–C data-integrated model elucidates <i>E. coli</i> chromosome’s multiscale organization at various replication stages
Abdul Wasim, Ankit Gupta, Jagannath Mondal
Publication Date: 28 February, 2021
Article Pages: 14 Open access contents
RNA thermoswitches modulate <i>Staphylococcus aureus</i> adaptation to ambient temperatures
Arancha Catalan-Moreno, Marta Cela, Pilar Menendez-Gil, Naiara Irurzun, Carlos J Caballero, Isabelle Caldelari, Alejandro Toledo-Arana
Publication Date: 28 February, 2021
Article Pages: 17 Open access contents
Complete minicircle genome of <i>Leptomonas pyrrhocoris</i> reveals sources of its non-canonical mitochondrial RNA editing events
Evgeny S Gerasimov, Anna A Gasparyan, Dmitry A Afonin, Sara L Zimmer, Natalya Kraeva, Julius Lukeš, Vyacheslav Yurchenko, Alexander Kolesnikov
Publication Date: 28 February, 2021
Article Pages: 16 Open access contents
Defining a novel domain that provides an essential contribution to site-specific interaction of Rep protein with DNA
Katarzyna Wegrzyn, Elzbieta Zabrocka, Katarzyna Bury, Bartlomiej Tomiczek, Milosz Wieczor, Jacek Czub, Urszula Uciechowska, María Moreno-del Alamo, Urszula Walkow, Igor Grochowina, Rafal Dutkiewicz, Janusz M Bujnicki, Rafael Giraldo, Igor Konieczny
Publication Date: 28 February, 2021
Article Pages: 14 Open access contents
Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity
Joshua T Burgess, Chee Man Cheong, Amila Suraweera, Thais Sobanski, Sam Beard, Keyur Dave, Maddison Rose, Didier Boucher, Laura V Croft, Mark N Adams, Kenneth O’Byrne, Derek J Richard, Emma Bolderson
Publication Date: 28 February, 2021
Article Pages: 13 Open access contents
Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects
Chengkun Wang, Jason K W Cheng, Qianhe Zhang, Nicholas W Hughes, Qiong Xia, Monte M Winslow, Le Cong
Publication Date: 22 February, 2021
Article Pages: 1 Open access contents
Mechanism of forkhead transcription factors binding to a novel palindromic DNA site
Jun Li, Shuyan Dai, Xiaojuan Chen, Xujun Liang, Lingzhi Qu, Longying Jiang, Ming Guo, Zhan Zhou, Hudie Wei, Huajun Zhang, Zhuchu Chen, Lin Chen, Yongheng Chen
Publication Date: 12 February, 2021
Article Pages: 10 Open access contents