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His345 mutant of angiotensin-converting enzyme 2 (ACE2) remains enzymatically active against angiotensin II
Pan Liu, Xinfang Xie, Li Gao, Jing Jin
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Article Pages: 1 Open access contents
Reply to Liu et al.: Specific mutations matter in specificity and catalysis in ACE2
Jeff Glasgow, Anum Glasgow, Tanja Kortemme, James A. Wells
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Article Pages: 1 Open access contents
Learning the molecular grammar of protein condensates from sequence determinants and embeddings
Kadi L. Saar, Alexey S. Morgunov, Runzhang Qi, William E. Arter, Georg Krainer, Alpha A. Lee, Tuomas P. J. Knowles
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Article Pages: 1 Open access contents
Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA
James R. Portman, Gwendolyn M. Brouwer, Jack Bollins, Nigel J. Savery, Terence R. Strick
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Article Pages: 1 Open access contents
Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, Rob Fergus
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Article Pages: 1 Open access contents
Topological defects produce kinks in biopolymer filament bundles
Valentin M. Slepukhin, Maximilian J. Grill, Qingda Hu, Elliot L. Botvinick, Wolfgang A. Wall, Alex J. Levine
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Article Pages: 1 Open access contents
Deep generative selection models of T and B cell receptor repertoires with soNNia
Giulio Isacchini, Aleksandra M. Walczak, Thierry Mora, Armita Nourmohammad
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Article Pages: 1 Open access contents
Artificial intelligence velocimetry and microaneurysm-on-a-chip for three-dimensional analysis of blood flow in physiology and disease
Shengze Cai, He Li, Fuyin Zheng, Fang Kong, Ming Dao, George Em Karniadakis, Subra Suresh
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Article Pages: 1 Open access contents
A localized adaptor protein performs distinct functions at the <i>Caulobacter</i> cell poles
Jiarui Wang, W. E. Moerner, Lucy Shapiro
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Article Pages: 1 Open access contents
Early-stage dynamics of chloride ion–pumping rhodopsin revealed by a femtosecond X-ray laser
Ji-Hye Yun, Xuanxuan Li, Jianing Yue, Jae-Hyun Park, Zeyu Jin, Chufeng Li, Hao Hu, Yingchen Shi, Suraj Pandey, Sergio Carbajo, Sébastien Boutet, Mark S. Hunter, Mengning Liang, Raymond G. Sierra, Thomas J. Lane, Liang Zhou, Uwe Weierstall, Nadia A. Zatsepin, Mio Ohki, Jeremy R. H. Tame, Sam-Yong Park, John C. H. Spence, Wenkai Zhang, Marius Schmidt, Weontae Lee, Haiguang Liu
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Article Pages: 1 Open access contents