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Design of multi-scale protein complexes by hierarchical building block fusion
Yang Hsia, Rubul Mout, William Sheffler, Natasha I. Edman, Ivan Vulovic, Young-Jun Park, Rachel L. Redler, Matthew J. Bick, Asim K. Bera, Alexis Courbet, Alex Kang, T. J. Brunette, Una Nattermann, Evelyn Tsai, Ayesha Saleem, Cameron M. Chow, Damian Ekiert, Gira Bhabha, David Veesler, David Baker
Publication Date: 16 April, 2021
Article Pages: 1 Open access contents
Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate
Francesca Rapino, Zhaoli Zhou, Ana Maria Roncero Sanchez, Marc Joiret, Christian Seca, Najla El Hachem, Gianluca Valenti, Sara Latini, Kateryna Shostak, Liesbet Geris, Ping Li, Gang Huang, Gabriel Mazzucchelli, Dominique Baiwir, Christophe J. Desmet, Alain Chariot, Michel Georges, Pierre Close
Publication Date: 15 April, 2021
Article Pages: 1 Open access contents
Modification of <i>N</i>-terminal α-amine of proteins via biomimetic <i>ortho-</i>quinone-mediated oxidation
Siyao Wang, Qingqing Zhou, Xiaoping Chen, Rong-Hua Luo, Yunxue Li, Xinliang Liu, Liu-Meng Yang, Yong-Tang Zheng, Ping Wang
Publication Date: 15 April, 2021
Article Pages: 1 Open access contents
A systematic approach to inserting split inteins for Boolean logic gate engineering and basal activity reduction
Trevor Y. H. Ho, Alexander Shao, Zeyu Lu, Harri Savilahti, Filippo Menolascina, Lei Wang, Neil Dalchau, Baojun Wang
Publication Date: 13 April, 2021
Article Pages: 1 Open access contents
Structural and functional insights into esterase-mediated macrolide resistance
Michał Zieliński, Jaeok Park, Barry Sleno, Albert M. Berghuis
Publication Date: 19 March, 2021
Article Pages: 1 Open access contents
Structure-guided insights into heterocyclic ring-cleavage catalysis of the non-heme Fe (II) dioxygenase NicX
Gongquan Liu, Yi-Lei Zhao, Fangyuan He, Peng Zhang, Xingyu Ouyang, Hongzhi Tang, Ping Xu
Publication Date: 26 February, 2021
Article Pages: 1 Open access contents
Calculating metalation in cells reveals CobW acquires Co<sup>II</sup> for vitamin B<sub>12</sub> biosynthesis while related proteins prefer Zn<sup>II</sup>
Tessa R. Young, Maria Alessandra Martini, Andrew W. Foster, Arthur Glasfeld, Deenah Osman, Richard J. Morton, Evelyne Deery, Martin J. Warren, Nigel J. Robinson
Publication Date: 19 February, 2021
Article Pages: 1 Open access contents
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
Georg Krainer, Timothy J. Welsh, Jerelle A. Joseph, Jorge R. Espinosa, Sina Wittmann, Ella de Csilléry, Akshay Sridhar, Zenon Toprakcioglu, Giedre Gudiškytė, Magdalena A. Czekalska, William E. Arter, Jordina Guillén-Boixet, Titus M. Franzmann, Seema Qamar, Peter St George-Hyslop, Anthony A. Hyman, Rosana Collepardo-Guevara, Simon Alberti, Tuomas P. J. Knowles
Publication Date: 17 February, 2021
Article Pages: 1 Open access contents
Quantifying and visualizing weak interactions between anions and proteins
Binhan Yu, Channing C. Pletka, Junji Iwahara
Publication Date: 28 December, 2020
Article Pages: 1 Open access contents
Supramolecular Bait to Trigger Non‐Equilibrium Co‐Assembly and Clearance of Aβ42
Te‐Haw Wu, Rai‐Hua Lai, Chun‐Nien Yao, Jyh‐Lyh Juang, Shu‐Yi Lin
Publication Date: 27 December, 2020
Article Pages: 3 Open access contents