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Bi‐allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis‐like disease
Kalliopi Sofou, Kolja Meier, Leslie E Sanderson, Debora Kaminski, Laia Montoliu‐Gaya, Emma Samuelsson, Maria Blomqvist, Lotta Agholme, Jutta Gärtner, Chris Mühlhausen, Niklas Darin, Tahsin Stefan Barakat, Lars Schlotawa, Tjakko van Ham, Jorge Asin Cayuela, Fredrik H Sterky
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Article Pages: 1 Open access contents
<i>VPS39</i>-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
Cajsa Davegårdh, Johanna Säll, Anna Benrick, Christa Broholm, Petr Volkov, Alexander Perfilyev, Tora Ida Henriksen, Yanling Wu, Line Hjort, Charlotte Brøns, Ola Hansson, Maria Pedersen, Jens U. Würthner, Klaus Pfeffer, Emma Nilsson, Allan Vaag, Elisabet Stener-Victorin, Karolina Pircs, Camilla Scheele, Charlotte Ling
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Article Pages: 1 Open access contents
Selectivity of mRNA degradation by autophagy in yeast
Shiho Makino, Tomoko Kawamata, Shintaro Iwasaki, Yoshinori Ohsumi
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Article Pages: 1 Open access contents
Neurodegenerative <i>VPS41</i> variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation
Reini E N van der Welle, Rebekah Jobling, Christian Burns, Paolo Sanza, Jan A van der Beek, Alfonso Fasano, Lan Chen, Fried J Zwartkruis, Susan Zwakenberg, Edward F Griffin, Corlinda ten Brink, Tineke Veenendaal, Nalan Liv, Conny M A van Ravenswaaij‐Arts, Henny H Lemmink, Rolph Pfundt, Susan Blaser, Carolina Sepulveda, Andres M Lozano, Grace Yoon, Teresa Santiago‐Sim, Cedric S Asensio, Guy A Caldwell, Kim A Caldwell, David Chitayat, Judith Klumperman
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Article Pages: 1 Open access contents
UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy
Min Ji Yoon, Boyoon Choi, Eun Jin Kim, Jiyeon Ohk, Chansik Yang, Yeon-Gil Choi, Jinyoung Lee, Chanhee Kang, Hyun Kyu Song, Yoon Ki Kim, Jae-Sung Woo, Yongcheol Cho, Eui-Ju Choi, Hosung Jung, Chungho Kim
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Article Pages: 1 Open access contents
The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen
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Article Pages: 1 Open access contents
α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation
Mariana Pavel, So Jung Park, Rebecca A. Frake, Sung Min Son, Marco M. Manni, Carla F. Bento, Maurizio Renna, Thomas Ricketts, Fiona M. Menzies, Radu Tanasa, David C. Rubinsztein
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Article Pages: 1 Open access contents
SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin
Saeed Mehrzadi, Mohammad Yahya Karimi, Alireza Fatemi, Russel J. Reiter, Azam Hosseinzadeh
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Article Pages: 1 Open access contents
mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264.7 mouse monocytes
Qin Luo, Yuzhen Son, Jingjing Kang, Yuchen Wu, Fengsun Wu, Yueqin Li, Qing Dong, Jun Wang, Chao Song, Hongrui Guo
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Article Pages: 1 Open access contents
Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11
Subhadip Mukhopadhyay, Douglas E. Biancur, Seth J. Parker, Keisuke Yamamoto, Robert S. Banh, Joao A. Paulo, Joseph D. Mancias, Alec C. Kimmelman
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Article Pages: 1 Open access contents