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Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites
Marina Kulik, Melissa Bothe, Gözde Kibar, Alisa Fuchs, Stefanie Schöne, Stefan Prekovic, Isabel Mayayo-Peralta, Ho-Ryun Chung, Wilbert Zwart, Christine Helsen, Frank Claessens, Sebastiaan H Meijsing
Publication Date: 22 March, 2021
Article Pages: 19 Open access contents
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway
Jia Shi, Tianxi Yu, Kai Song, Shihan Du, Simeng He, Xinxin Hu, Xiangyun Li, Haibo Li, Shuan Dong, Yuan Zhang, Zilei Xie, Cui Li, Jianbo Yu
Publication Date: 21 March, 2021
Article Pages: 1 Open access contents
Regulator-dependent temporal dynamics of a restriction-modification system's gene expression upon entering new host cells: single-cell and population studies
Alessandro Negri, Olesia Werbowy, Ewa Wons, Simon Dersch, Rebecca Hinrichs, Peter L Graumann, Iwona Mruk
Publication Date: 21 March, 2021
Article Pages: 14 Open access contents
Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners
Agathe Marcelot, Ambre Petitalot, Virginie Ropars, Marie-Hélène Le Du, Camille Samson, Stevens Dubois, Guillaume Hoffmann, Simona Miron, Philippe Cuniasse, Jose Antonio Marquez, Robert Thai, François-Xavier Theillet, Sophie Zinn-Justin
Publication Date: 21 March, 2021
Article Pages: 14 Open access contents
Oligomeric quaternary structure of <i>Escherichia coli</i> and <i>Mycobacterium smegmatis</i> Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules
Garrett M Warren, Juncheng Wang, Dinshaw J Patel, Stewart Shuman
Publication Date: 21 March, 2021
Article Pages: 11 Open access contents
Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension
Daniel Duzdevich, Christopher E Carr, Dian Ding, Stephanie J Zhang, Travis S Walton, Jack W Szostak
Publication Date: 21 March, 2021
Article Pages: 10 Open access contents
Iron–sulfur biology invades tRNA modification: the case of U34 sulfuration
Jingjing Zhou, Marine Lénon, Jean-Luc Ravanat, Nadia Touati, Christophe Velours, Karolina Podskoczyj, Grazyna Leszczynska, Marc Fontecave, Frédéric Barras, Béatrice Golinelli-Pimpaneau
Publication Date: 21 March, 2021
Article Pages: 10 Open access contents
MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of <i>GNRH1</i> mRNA in mammalian puberty
Chuanyin Li, Tianting Han, Qingrun Li, Menghuan Zhang, Rong Guo, Yun Yang, Wenli Lu, Zhengwei Li, Chao Peng, Ping Wu, Xiaoxu Tian, Qinqin Wang, Yuexiang Wang, Vincent Zhou, Ziyan Han, Hecheng Li, Feng Wang, Ronggui Hu
Publication Date: 21 March, 2021
Article Pages: 17 Open access contents
An RNA-binding protein complex regulates the purine-dependent expression of a nucleobase transporter in trypanosomes
Miriam Rico-Jiménez, Gloria Ceballos-Pérez, Claudia Gómez-Liñán, Antonio M Estévez
Publication Date: 21 March, 2021
Article Pages: 11 Open access contents
Systematic <i>in vitro</i> specificity profiling reveals nicking defects in natural and engineered CRISPR–Cas9 variants
Karthik Murugan, Shravanti K Suresh, Arun S Seetharam, Andrew J Severin, Dipali G Sashital
Publication Date: 21 March, 2021
Article Pages: 16 Open access contents