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Rational engineering of a modular bacterial CRISPR–Cas activation platform with expanded target range
Maria Claudia Villegas Kcam, Annette J Tsong, James Chappell
Publication Date: 06 April, 2021
Article Pages: 9 Open access contents
Choice of fluorophore affects dynamic DNA nanostructures
Kevin Jahnke, Helmut Grubmüller, Maxim Igaev, Kerstin Göpfrich
Publication Date: 30 March, 2021
Article Pages: 9 Open access contents
MiniCAFE, a CRISPR/Cas9-based compact and potent transcriptional activator, elicits gene expression <i>in vivo</i>
Xin Zhang, Sihan Lv, Zhenhuan Luo, Yongfei Hu, Xin Peng, Jie Lv, Shanshan Zhao, Jianqi Feng, Guanjie Huang, Qin-Li Wan, Jun Liu, Hongxin Huang, Bing Luan, Dong Wang, Xiaoyang Zhao, Ying Lin, Qinghua Zhou, Zhen-Ning Zhang, Zhili Rong
Publication Date: 22 March, 2021
Article Pages: 14 Open access contents
Targeted-antibacterial-plasmids (TAPs) combining conjugation and CRISPR/Cas systems achieve strain-specific antibacterial activity
Audrey Reuter, Cécile Hilpert, Annick Dedieu-Berne, Sophie Lematre, Erwan Gueguen, Guillaume Launay, Sarah Bigot, Christian Lesterlin
Publication Date: 28 February, 2021
Article Pages: 14 Open access contents
Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing
Ha Rim Shin, Ji-Eun See, Jiyeon Kweon, Heon Seok Kim, Gi-Jun Sung, Sojung Park, An-Hee Jang, Gayoung Jang, Kyung‐Chul Choi, Inki Kim, Jin-Soo Kim, Yongsub Kim
Publication Date: 05 February, 2021
Article Pages: 9 Open access contents
Ligand-dependent tRNA processing by a rationally designed RNase P riboswitch
Anna Ender, Maja Etzel, Stefan Hammer, Sven Findeiß, Peter Stadler, Mario Mörl
Publication Date: 19 January, 2021
Article Pages: 16 Open access contents
A supernumerary designer chromosome for modular <i>in vivo</i> pathway assembly in <i>Saccharomyces cerevisiae</i>
Eline D Postma, Sofia Dashko, Lars van Breemen, Shannara K Taylor Parkins, Marcel van den Broek, Jean-Marc Daran, Pascale Daran-Lapujade
Publication Date: 11 January, 2021
Article Pages: 14 Open access contents
Precise and broad scope genome editing based on high-specificity Cas9 nickases
Qian Wang, Jin Liu, Josephine M Janssen, Marie Le Bouteiller, Richard L Frock, Manuel A F V Gonçalves
Publication Date: 04 January, 2021
Article Pages: 25 Open access contents
Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites
Tiebin Wang, Nathan Tague, Stephen A Whelan, Mary J Dunlop
Publication Date: 24 December, 2020
Article Pages: 9 Open access contents