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Iron–sulfur biology invades tRNA modification: the case of U34 sulfuration
Jingjing Zhou, Marine Lénon, Jean-Luc Ravanat, Nadia Touati, Christophe Velours, Karolina Podskoczyj, Grazyna Leszczynska, Marc Fontecave, Frédéric Barras, Béatrice Golinelli-Pimpaneau
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Article Pages: 10 Open access contents
Systematic <i>in vitro</i> specificity profiling reveals nicking defects in natural and engineered CRISPR–Cas9 variants
Karthik Murugan, Shravanti K Suresh, Arun S Seetharam, Andrew J Severin, Dipali G Sashital
Publication Date:
Article Pages: 16 Open access contents
A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium <i>Kurthia massiliensis</i>
Ekaterina Kropocheva, Anton Kuzmenko, Alexei A Aravin, Daria Esyunina, Andrey Kulbachinskiy
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Article Pages: 11 Open access contents
Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity
Ziying Hu, Chengdong Zhang, Shuai Wang, Siqi Gao, Jingjing Wei, Miaomiao Li, Linghui Hou, Huilin Mao, Yanyan Wei, Tao Qi, Hongmao Liu, Dong Liu, Feng Lan, Daru Lu, Hongyan Wang, Jixi Li, Yongming Wang
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Article Pages: 11 Open access contents
Regulation of RNA editing by intracellular acidification
Turnee N Malik, Erin E Doherty, Vandana M Gaded, Theodore M Hill, Peter A Beal, Ronald B Emeson
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Article Pages: 16 Open access contents
Oligomeric complexes formed by Redβ single strand annealing protein in its different DNA bound states
Brian J Caldwell, Andrew Norris, Ekaterina Zakharova, Christopher E Smith, Carter T Wheat, Deepanshu Choudhary, Marcos Sotomayor, Vicki H Wysocki, Charles E Bell
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Article Pages: 19 Open access contents
A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol
Kazutoshi Kasho, Gorazd Stojkovič, Cristina Velázquez-Ruiz, Maria Isabel Martínez-Jiménez, Mara Doimo, Timothée Laurent, Andreas Berner, Aldo E Pérez-Rivera, Louise Jenninger, Luis Blanco, Sjoerd Wanrooij
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Article Pages: 12 Open access contents
Mechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in <i>Staphylococcus aureus</i>
Vinayak Sadasivam Tumuluri, Vrunda Rajgor, Shuang-Yong Xu, Om Prakash Chouhan, Kayarat Saikrishnan
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Article Pages: 17 Open access contents
Structure of a reaction intermediate mimic in t<sup>6</sup>A biosynthesis bound in the active site of the TsaBD heterodimer from <i>Escherichia coli</i>
Brett J Kopina, Sophia Missoury, Bruno Collinet, Mark G Fulton, Charles Cirio, Herman van Tilbeurgh, Charles T Lauhon
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Article Pages: 19 Open access contents
Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism
Gyanendra Kumar, Maxime Cuypers, Richard R Webby, Thomas R Webb, Stephen W White
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Article Pages: 9 Open access contents