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The ATR-WEE1 kinase module inhibits the MAC complex to regulate replication stress response
Lili Wang, Li Zhan, Yan Zhao, Yongchi Huang, Chong Wu, Ting Pan, Qi Qin, Yiren Xu, Zhiping Deng, Jing Li, Honghong Hu, Shaowu Xue, Shunping Yan
Publication Date:
Article Pages: 14 Open access contents
The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes
Ann-Kathrin Mehnert, Marco Prorocic, Annick Dujeancourt-Henry, Sebastian Hutchinson, Richard McCulloch, Lucy Glover
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Article Pages: 18 Open access contents
Allosteric effects of SSB C-terminal tail on assembly of <i>E. coli</i> RecOR proteins
Min Kyung Shinn, Alexander G Kozlov, Timothy M Lohman
Publication Date:
Article Pages: 17 Open access contents
Hydrogen–deuterium exchange reveals a dynamic DNA-binding map of replication protein A
Faiz Ahmad, Angela Patterson, Jaigeeth Deveryshetty, Jenna R Mattice, Nilisha Pokhrel, Brian Bothner, Edwin Antony
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Article Pages: 14 Open access contents
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation
Miłosz Roliński, Nicola Pietro Montaldo, Merdane Ezgi Aksu, Sarah L Fordyce Martin, Alessandro Brambilla, Nicolas Kunath, Jostein Johansen, Sten Even Erlandsen, Nina-Beate Liabbak, Kristin Rian, Magnar Bjørås, Pål Sætrom, Barbara van Loon
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Article Pages: 14 Open access contents
SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection
Andrew J Locke, Lazina Hossain, Glynnis McCrostie, Daryl A Ronato, Amira Fitieh, Tanzeem Ahmed Rafique, Fatemeh Mashayekhi, Mobina Motamedi, Jean-Yves Masson, Ismail Hassan Ismail
Publication Date:
Article Pages: 25 Open access contents
A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks
Talia Hatkevich, Danny E Miller, Carolyn A Turcotte, Margaret C Miller, Jeff Sekelsky
Publication Date:
Article Pages: 11 Open access contents
Catalytically inactive Cas9 impairs DNA replication fork progression to induce focal genomic instability
Goro Doi, Satoshi Okada, Takehiro Yasukawa, Yuki Sugiyama, Siqin Bala, Shintaro Miyazaki, Dongchon Kang, Takashi Ito
Publication Date:
Article Pages: 14 Open access contents
Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing
Ya-Wen Fu, Xin-Yue Dai, Wen-Tian Wang, Zhi-Xue Yang, Juan-Juan Zhao, Jian-Ping Zhang, Wei Wen, Feng Zhang, Kerby C Oberg, Lei Zhang, Tao Cheng, Xiao-Bing Zhang
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Article Pages: 16 Open access contents
Chromatin structure restricts origin utilization when quiescent cells re-enter the cell cycle
Po-Hsuen Lee, Mary Ann Osley
Publication Date:
Article Pages: 14 Open access contents