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Delivery of oligonucleotide‐based therapeutics: challenges and opportunities
Suzan M Hammond, Annemieke Aartsma‐Rus, Sandra Alves, Sven E Borgos, Ronald A M Buijsen, Rob W J Collin, Giuseppina Covello, Michela A Denti, Lourdes R Desviat, Lucía Echevarría, Camilla Foged, Gisela Gaina, Alejandro Garanto, Aurelie T Goyenvalle, Magdalena Guzowska, Irina Holodnuka, David R Jones, Sabine Krause, Taavi Lehto, Marisol Montolio, Willeke Van Roon‐Mom, Virginia Arechavala‐Gomeza
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Article Pages: 1 Open access contents
The RNA polymerase II subunit RPB‐9 recruits the integrator complex to terminate <i>Caenorhabditis elegans</i> piRNA transcription
Ahmet C Berkyurek, Giulia Furlan, Lisa Lampersberger, Toni Beltran, Eva‐Maria Weick, Emily Nischwitz, Isabela Cunha Navarro, Fabian Braukmann, Alper Akay, Jonathan Price, Falk Butter, Peter Sarkies, Eric A Miska
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Article Pages: 1 Open access contents
Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in <i>Drosophila</i>
Lina Worpenberg, Chiara Paolantoni, Sara Longhi, Miriam M Mulorz, Tina Lence, Hans‐Hermann Wessels, Erik Dassi, Giuseppe Aiello, F X Reymond Sutandy, Marion Scheibe, Raghu R Edupuganti, Anke Busch, Martin M Möckel, Michiel Vermeulen, Falk Butter, Julian König, Michela Notarangelo, Uwe Ohler, Christoph Dieterich, Alessandro Quattrone, Alessia Soldano, Jean‐Yves Roignant
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Article Pages: 1 Open access contents
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
Veronica H Ryan, Theodora M Perdikari, Mandar T Naik, Camillo F Saueressig, Jeremy Lins, Gregory L Dignon, Jeetain Mittal, Anne C Hart, Nicolas L Fawzi
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Article Pages: 1 Open access contents
Integrator is recruited to promoter‐proximally paused RNA Pol II to generate <i>Caenorhabditis elegans</i> piRNA precursors
Toni Beltran, Elena Pahita, Subhanita Ghosh, Boris Lenhard, Peter Sarkies
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Article Pages: 1 Open access contents
Translation is required for miRNA‐dependent decay of endogenous transcripts
Adriano Biasini, Baroj Abdulkarim, Stefano de Pretis, Jennifer Y Tan, Rajika Arora, Harry Wischnewski, Rene Dreos, Mattia Pelizzola, Constance Ciaudo, Ana Claudia Marques
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Article Pages: 1 Open access contents
Intrinsically disordered protein PID‐2 modulates Z granules and is required for heritable piRNA‐induced silencing in the <i>Caenorhabditis elegans</i> embryo
Maria Placentino, António Miguel de Jesus Domingues, Jan Schreier, Sabrina Dietz, Svenja Hellmann, Bruno FM de Albuquerque, Falk Butter, René F Ketting
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Article Pages: 1 Open access contents