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Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4
Lisa M. Tuttle, Derek Pacheco, Linda Warfield, Damien B. Wilburn, Steven Hahn, Rachel E. Klevit
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Article Pages: 1 Open access contents
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry
N. Tavernier, Y. Thomas, S. Vigneron, P. Maisonneuve, S. Orlicky, P. Mader, S. G. Regmi, L. Van Hove, N. M. Levinson, G. Gasmi-Seabrook, N. Joly, M. Poteau, G. Velez-Aguilera, O. Gavet, A. Castro, M. Dasso, T. Lorca, F. Sicheri, L. Pintard
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Article Pages: 1 Open access contents
Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
Álvaro Rol, Toni Todorovski, Pau Martin-Malpartida, Anna Escolà, Elena Gonzalez-Rey, Eric Aragón, Xavier Verdaguer, Mariona Vallès-Miret, Josep Farrera-Sinfreu, Eduard Puig, Jimena Fernández-Carneado, Berta Ponsati, Mario Delgado, Antoni Riera, Maria J. Macias
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Article Pages: 1 Open access contents
A Solid‐State Intramolecular Wittig Reaction Enables Efficient Synthesis of Endofullerenes Including Ne@C<sub>60</sub>, <sup>3</sup>He@C<sub>60</sub>, and HD@C<sub>60</sub>
Gabriela Hoffman, Mark C. Walkey, John Gräsvik, George R. Bacanu, Shamim Alom, Sally Bloodworth, Mark E. Light, Malcolm H. Levitt, Richard J. Whitby
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Article Pages: 6 Open access contents
A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins
T Reid Alderson, Elias Adriaenssens, Bob Asselbergh, Iva Pritišanac, Jonas Van Lent, Heidi Y Gastall, Marielle A Wälti, John M Louis, Vincent Timmerman, Andrew J Baldwin, Justin LP Benesch
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Article Pages: 1 Open access contents
Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone
Bryan D. Ryder, Irina Matlahov, Sofia Bali, Jaime Vaquer-Alicea, Patrick C. A. van der Wel, Lukasz A. Joachimiak
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Article Pages: 1 Open access contents
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
Wing K. Man, Bogachan Tahirbegi, Michail D. Vrettas, Swapan Preet, Liming Ying, Michele Vendruscolo, Alfonso De Simone, Giuliana Fusco
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Article Pages: 1 Open access contents
Mechanism of the small ATP-independent chaperone Spy is substrate specific
Rishav Mitra, Varun V. Gadkari, Ben A. Meinen, Carlo P. M. van Mierlo, Brandon T. Ruotolo, James C. A. Bardwell
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Article Pages: 1 Open access contents
Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
Parker J. Nichols, Shaun Bevers, Morkos Henen, Jeffrey S. Kieft, Quentin Vicens, Beat Vögeli
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Article Pages: 1 Open access contents
In situ NMR reveals real-time nanocrystal growth evolution via monomer-attachment or particle-coalescence
Reut Mashiach, Haim Weissman, Liat Avram, Lothar Houben, Olga Brontvein, Anna Lavie, Vaishali Arunachalam, Michal Leskes, Boris Rybtchinski, Amnon Bar-Shir
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Article Pages: 1 Open access contents