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Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
Simon Bo Jensen, Sara Thodberg, Shaheena Parween, Matias E. Moses, Cecilie C. Hansen, Johannes Thomsen, Magnus B. Sletfjerding, Camilla Knudsen, Rita Del Giudice, Philip M. Lund, Patricia R. Castaño, Yanet G. Bustamante, Maria Natalia Rojas Velazquez, Flemming Steen Jørgensen, Amit V. Pandey, Tomas Laursen, Birger Lindberg Møller, Nikos S. Hatzakis
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Article Pages: 1 Open access contents
Direct 1,3-butadiene biosynthesis in <i>Escherichia coli</i> via a tailored ferulic acid decarboxylase mutant
Yutaro Mori, Shuhei Noda, Tomokazu Shirai, Akihiko Kondo
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Article Pages: 1 Open access contents
Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
Majid Haddad Momeni, Folmer Fredslund, Bastien Bissaro, Olanrewaju Raji, Thu V. Vuong, Sebastian Meier, Tine Sofie Nielsen, Vincent Lombard, Bruno Guigliarelli, Frédéric Biaso, Mireille Haon, Sacha Grisel, Bernard Henrissat, Ditte Hededam Welner, Emma R. Master, Jean-Guy Berrin, Maher Abou Hachem
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Article Pages: 1 Open access contents
Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide
Xueying Wang, Yanbin Feng, Xiaojia Guo, Qian Wang, Siyang Ning, Qing Li, Junting Wang, Lei Wang, Zongbao K. Zhao
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Article Pages: 1 Open access contents
A [6+4]-cycloaddition adduct is the biosynthetic intermediate in streptoseomycin biosynthesis
Kai Biao Wang, Wen Wang, Bo Zhang, Xin Wang, Yu Chen, Hong Jie Zhu, Yong Liang, Ren Xiang Tan, Hui Ming Ge
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Article Pages: 1 Open access contents
Asymmetric Synthesis of <i>N</i>‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination
Peiyuan Yao, James R. Marshall, Zefei Xu, Jesmine Lim, Simon J. Charnock, Dunming Zhu, Nicholas J. Turner
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Article Pages: 4 Open access contents
Responsive Emulsions for Sequential Multienzyme Cascades
Zhiyong Sun, Qingcai Zhao, Rainer Haag, Changzhu Wu
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Article Pages: 4 Open access contents
Fungal Dioxygenase AsqJ Is Promiscuous and Bimodal: Substrate‐Directed Formation of Quinolones versus Quinazolinones
Manuel Einsiedler, Cooper S. Jamieson, Mark A. Maskeri, Kendall N. Houk, Tobias A. M. Gulder
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Article Pages: 5 Open access contents
Active-site loop variations adjust activity and selectivity of the cumene dioxygenase
Peter M. Heinemann, Daniel Armbruster, Bernhard Hauer
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Article Pages: 1 Open access contents
The power of electrified nanoconfinement for energising, controlling and observing long enzyme cascades
Giorgio Morello, Clare F. Megarity, Fraser A. Armstrong
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Article Pages: 1 Open access contents