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Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects
Chengkun Wang, Jason K W Cheng, Qianhe Zhang, Nicholas W Hughes, Qiong Xia, Monte M Winslow, Le Cong
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Article Pages: 1 Open access contents
Flexible comparison of batch correction methods for single-cell RNA-seq using BatchBench
Ruben Chazarra-Gil, Stijn van Dongen, Vladimir Yu Kiselev, Martin Hemberg
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Article Pages: 1 Open access contents
DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing
Arjun Bhattacharya, Alina M Hamilton, Melissa A Troester, Michael I Love
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Article Pages: 1 Open access contents
The loopometer: a quantitative <i>in vivo</i> assay for DNA-looping proteins
Nan Hao, Adrienne E Sullivan, Keith E Shearwin, Ian B Dodd
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Article Pages: 1 Open access contents
Solid-phase XRN1 reactions for RNA cleavage: application in single-molecule sequencing
Uditha S Athapattu, Charuni A Amarasekara, Jacob R Immel, Steven Bloom, Francis Barany, Aaron C Nagel, Steven A Soper
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Article Pages: 1 Open access contents
Single cell epigenetic visualization assay
Sam Kint, Wim Van Criekinge, Linos Vandekerckhove, Winnok H De Vos, Karol Bomsztyk, Diane S Krause, Oleg Denisenko
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Article Pages: 1 Open access contents
A benchmark and an algorithm for detecting germline transposon insertions and measuring <i>de novo</i> transposon insertion frequencies
Tianxiong Yu, Xiao Huang, Shengqian Dou, Xiaolu Tang, Shiqi Luo, William E Theurkauf, Jian Lu, Zhiping Weng
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Article Pages: 1 Open access contents
A novel all-in-one conditional knockout system uncovered an essential role of DDX1 in ribosomal RNA processing
Teruhiko Suzuki, Eiji Katada, Yuki Mizuoka, Satoko Takagi, Yasuhiro Kazuki, Mitsuo Oshimura, Mayumi Shindo, Takahiko Hara
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Article Pages: 1 Open access contents
DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism
Duolin Wang, Zhaoyue Zhang, Yuexu Jiang, Ziting Mao, Dong Wang, Hao Lin, Dong Xu
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Article Pages: 1 Open access contents
Nebula: ultra-efficient mapping-free structural variant genotyper
Parsoa Khorsand, Fereydoun Hormozdiari
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Article Pages: 1 Open access contents