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Quantifying the dose-dependent impact of intracellular amyloid beta in a mathematical model of calcium regulation in xenopus oocyte
Joseph Minicucci, Molly Alfond, Angelo Demuro, David Gerberry, Joe Latulippe
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Article Pages: 1 Open access contents
Evaluating Deep Learning models for predicting ALK-5 inhibition
Gabriel Z. Espinoza, Rafaela M. Angelo, Patricia R. Oliveira, Kathia M. Honorio
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Article Pages: 1 Open access contents
Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers
Jonas Béal, Lorenzo Pantolini, Vincent Noël, Emmanuel Barillot, Laurence Calzone
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Article Pages: 1 Open access contents
Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model
Vikas Pandey, Lai-Hua Xie, Zhilin Qu, Zhen Song
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Article Pages: 1 Open access contents
Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence
Cullen Roth, Debra Murray, Alexandria Scott, Ci Fu, Anna F. Averette, Sheng Sun, Joseph Heitman, Paul M. Magwene
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Article Pages: 1 Open access contents
MEK/ERK signaling is a critical regulator of high-risk human papillomavirus oncogene expression revealing therapeutic targets for HPV-induced tumors
Adrian J. Luna, Rosa T. Sterk, Anastacia M. Griego-Fisher, Joon-Yong Chung, Kiersten L. Berggren, Virginie Bondu, Pamela Barraza-Flores, Andrew T. Cowan, Gregory N. Gan, Emrullah Yilmaz, Hanbyoul Cho, Jae-Hoon Kim, Stephen M. Hewitt, Julie E. Bauman, Michelle A. Ozbun
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Article Pages: 1 Open access contents
The BMP signaling gradient is interpreted through concentration thresholds in dorsal–ventral axial patterning
Hannah Greenfeld, Jerome Lin, Mary C. Mullins
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Article Pages: 1 Open access contents
Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways
Chen-Yi Tang, Mengrui Wu, Dongfeng Zhao, Diep Edwards, Abigail McVicar, Yuan Luo, Guochun Zhu, Yongjun Wang, Hou-De Zhou, Wei Chen, Yi-Ping Li
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Article Pages: 1 Open access contents
PI3k inhibitors (BKM120 and BYL719) as radiosensitizers for head and neck squamous cell carcinoma during radiotherapy
Fu-Cheng Chuang, Chih-Chun Wang, Jian-Han Chen, Tzer-Zen Hwang, Shyh-An Yeh, Yu-Chieh Su
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Article Pages: 1 Open access contents
A workflow for sizing oligomeric biomolecules based on cryo single molecule localization microscopy
Magdalena C. Schneider, Roger Telschow, Gwenael Mercier, Montserrat López-Martinez, Otmar Scherzer, Gerhard J. Schütz
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Article Pages: 1 Open access contents