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Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing
Antoine Cléry, Miroslav Krepl, Cristina K. X. Nguyen, Ahmed Moursy, Hadi Jorjani, Maria Katsantoni, Michal Okoniewski, Nitish Mittal, Mihaela Zavolan, Jiri Sponer, Frédéric H.-T. Allain
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Male fertility in <i>Arabidopsis</i> requires active DNA demethylation of genes that control pollen tube function
Souraya Khouider, Filipe Borges, Chantal LeBlanc, Alexander Ungru, Arp Schnittger, Robert Martienssen, Vincent Colot, Daniel Bouyer
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Mathematical model of COVID-19 intervention scenarios for São Paulo—Brazil
Osmar Pinto Neto, Deanna M. Kennedy, José Clark Reis, Yiyu Wang, Ana Carolina Brisola Brizzi, Gustavo José Zambrano, Joabe Marcos de Souza, Wellington Pedroso, Rodrigo Cunha de Mello Pedreiro, Bruno de Matos Brizzi, Ellysson Oliveira Abinader, Renato Amaro Zângaro
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming
Yao Wang, Chuan Tong, Hanren Dai, Zhiqiang Wu, Xiao Han, Yelei Guo, Deyun Chen, Jianshu Wei, Dongdong Ti, Zongzhi Liu, Qian Mei, Xiang Li, Liang Dong, Jing Nie, Yajing Zhang, Weidong Han
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Quantifying neurotransmitter secretion at single-vesicle resolution using high-density complementary metal–oxide–semiconductor electrode array
Kevin A. White, Brian N. Kim
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Dll1<sup>+</sup> quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway
Sushil Kumar, Ajeya Nandi, Snahlata Singh, Rohan Regulapati, Ning Li, John W. Tobias, Christian W. Siebel, Mario Andres Blanco, Andres J. Klein-Szanto, Christopher Lengner, Alana L. Welm, Yibin Kang, Rumela Chakrabarti
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Structural analysis of cross α-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials
Fengbin Wang, Ordy Gnewou, Charles Modlin, Leticia C. Beltran, Chunfu Xu, Zhangli Su, Puneet Juneja, Gevorg Grigoryan, Edward H. Egelman, Vincent P. Conticello
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy
Divija Deshpande, Nitin Agarwal, Thomas Fleming, Claire Gaveriaux-Ruff, Christoph S. N. Klose, Anke Tappe-Theodor, Rohini Kuner, Peter Nawroth
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Observation and control of the weak topological insulator state in ZrTe<sub>5</sub>
Peng Zhang, Ryo Noguchi, Kenta Kuroda, Chun Lin, Kaishu Kawaguchi, Koichiro Yaji, Ayumi Harasawa, Mikk Lippmaa, Simin Nie, Hongming Weng, V. Kandyba, A. Giampietri, A. Barinov, Qiang Li, G. D. Gu, Shik Shin, Takeshi Kondo
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
Pojeong Park, John Georgiou, Thomas M. Sanderson, Kwang-Hee Ko, Heather Kang, Ji-il Kim, Clarrisa A. Bradley, Zuner A. Bortolotto, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Ionic shape-morphing microrobotic end-effectors for environmentally adaptive targeting, releasing, and sampling
Zhiqiang Zheng, Huaping Wang, Lixin Dong, Qing Shi, Jianing Li, Tao Sun, Qiang Huang, Toshio Fukuda
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Soliton microcomb based spectral domain optical coherence tomography
Paul J. Marchand, Johann Riemensberger, J. Connor Skehan, Jia-Jung Ho, Martin H. P. Pfeiffer, Junqiu Liu, Christoph Hauger, Theo Lasser, Tobias J. Kippenberg
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Role of dams in reducing global flood exposure under climate change
Julien Boulange, Naota Hanasaki, Dai Yamazaki, Yadu Pokhrel
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Publisher Correction: Magnetic field detection limits for ultraclean graphene Hall sensors
Brian T. Schaefer, Lei Wang, Alexander Jarjour, Kenji Watanabe, Takashi Taniguchi, Paul L. McEuen, Katja C. Nowack
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
Contact-independent killing mediated by a T6SS effector with intrinsic cell-entry properties
Li Song, Junfeng Pan, Yantao Yang, Zhenxing Zhang, Rui Cui, Shuangkai Jia, Zhuo Wang, Changxing Yang, Lei Xu, Tao G. Dong, Yao Wang, Xihui Shen
Publication Date: 18 January, 2021
Article Pages: 1 Open access contents
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