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Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis

Hudie Wei, Lingzhi Qu, Shuyan Dai, Yun Li, Haolan Wang, Yilu Feng, Xiaojuan Chen, Longying Jiang, Ming Guo, Jun Li, Zhuchu Chen, Lin Chen, Ye Zhang, Yongheng Chen

Publication Date: 2021-04-16T00:00

Article Pages: 1

Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

Kyle Rosenke, Frederick Hansen, Benjamin Schwarz, Friederike Feldmann, Elaine Haddock, Rebecca Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, Heinz Feldmann, Michael A. Jarvis

Publication Date: 2021-04-16T00:00

Article Pages: 1

<i>O</i>-linked <i>N</i>-acetylglucosamine transferase is involved in fine regulation of flowering time in winter wheat

O-linked N-acetylglucosamine transferase is involved in fine regulation of flowering time in winter wheat

Min Fan, Fang Miao, Haiyan Jia, Genqiao Li, Carol Powers, Ragupathi Nagarajan, Phillip D. Alderman, Brett F. Carver, Zhengqiang Ma, Liuling Yan

Publication Date: 2021-04-16T00:00

Article Pages: 1

Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer

Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano

Publication Date: 2021-04-16T00:00

Article Pages: 1

Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity

Jianan Li, Wenxia Yu, Shisheng Huang, Susu Wu, Liping Li, Jiankui Zhou, Yu Cao, Xingxu Huang, Yunbo Qiao

Publication Date: 2021-04-16T00:00

Article Pages: 1

Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease

Stephen Watt, Louella Vasquez, Klaudia Walter, Alice L. Mann, Kousik Kundu, Lu Chen, Ying Sims, Simone Ecker, Frances Burden, Samantha Farrow, Ben Farr, Valentina Iotchkova, Heather Elding, Daniel Mead, Manuel Tardaguila, Hannes Ponstingl, David Richardson, Avik Datta, Paul Flicek, Laura Clarke, Kate Downes, Tomi Pastinen, Peter Fraser, Mattia Frontini, Biola-Maria Javierre, Mikhail Spivakov, Nicole Soranzo

Publication Date: 2021-04-16T00:00

Article Pages: 1

Classical MHC expression by DP thymocytes impairs the selection of non-classical MHC restricted innate-like T cells

Hristo Georgiev, Changwei Peng, Matthew A. Huggins, Stephen C. Jameson, Kristin A. Hogquist

Publication Date: 2021-04-16T00:00

Article Pages: 1

TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation

Ei’ichi Iizasa, Yasushi Chuma, Takayuki Uematsu, Mio Kubota, Hiroaki Kawaguchi, Masayuki Umemura, Kenji Toyonaga, Hideyasu Kiyohara, Ikuya Yano, Marco Colonna, Masahiko Sugita, Goro Matsuzaki, Sho Yamasaki, Hiroki Yoshida, Hiromitsu Hara

Publication Date: 2021-04-16T00:00

Article Pages: 1