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Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase
Matthew R. Freidel, Roger S. Armen
Publication Date: 17 February, 2021
Article Pages: 1 Open access contents
Marek’s disease virus U<sub>S</sub>3 protein kinase phosphorylates chicken HDAC 1 and 2 and regulates viral replication and pathogenesis
Yifei Liao, Blanca Lupiani, Mohammad AI-Mahmood, Sanjay M. Reddy
Publication Date: 17 February, 2021
Article Pages: 1 Open access contents
Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy
Irene Pila-Castellanos, Diana Molino, Joe McKellar, Laetitia Lines, Juliane Da Graca, Marine Tauziet, Laurent Chanteloup, Ivan Mikaelian, Laurène Meyniel-Schicklin, Patrice Codogno, Jacky Vonderscher, Cédric Delevoye, Olivier Moncorgé, Eric Meldrum, Caroline Goujon, Etienne Morel, Benoit de Chassey
Publication Date: 17 February, 2021
Article Pages: 1 Open access contents
23-valent polysaccharide vaccine (PPSV23)-targeted serotype-specific identification of <i>Streptococcus pneumoniae</i> using the loop-mediated isothermal amplification (LAMP) method
Jiwon Lee, Youngbae Yoon, Eun Jin Kim, Donghyun Lee, Yeongjun Baek, Chika Takano, Bin Chang, Takahiro Iijima, Paul E. Kilgore, Satoshi Hayakawa, Tomonori Hoshino, Dong Wook Kim, Mitsuko Seki
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
Non-permissive human conventional CD1c<sup>+</sup> dendritic cells enable <i>trans</i>-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization
Mathieu Sikorski, Flora Coulon, Cécile Peltier, Cécile Braudeau, Alexandra Garcia, Matthieu Giraud, Karine Renaudin, Christine Kandel-Aznar, Steven Nedellec, Philippe Hulin, Julien Branchereau, Joëlle Véziers, Pauline Gaboriaud, Antoine Touzé, Julien Burlaud-Gaillard, Régis Josien, Dorian McIlroy, Céline Bressollette-Bodin, Franck Halary
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation
Steven Andrew Baker, Shirley Kwok, Gerald J. Berry, Thomas J. Montine
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in <i>Aedes aegypti</i> Aag2 cells
Tiffany A. Russell, Andalus Ayaz, Andrew D. Davidson, Ana Fernandez-Sesma, Kevin Maringer
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
Ulcerative skin lesions among children in Cameroon: It is not always Yaws
Jean-Philippe Ndzomo Ngono, Serges Tchatchouang, Mireille Victorine Noah Tsanga, Earnest Njih Tabah, Albert Tchualeu, Kingsley Asiedu, Lorenzo Giacani, Sara Eyangoh, Tania Crucitti
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
Eukaryotic translation initiation factor 5A and its posttranslational modifications play an important role in proliferation and potentially in differentiation of the human enteric protozoan parasite <i>Entamoeba histolytica</i>
Ghulam Jeelani, Tomoyoshi Nozaki
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
The PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation
Yan Zeng, Shuai Xu, Yanli Wei, Xuegang Zhang, Qian Wang, Yane Jia, Wanbing Wang, Lu Han, Zhaoshan Chen, Zhengxiang Wang, Bo Zhang, Hualan Chen, Cao-Qi Lei, Qiyun Zhu
Publication Date: 12 February, 2021
Article Pages: 1 Open access contents
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