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SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration
Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio
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Article Pages: 1 Open access contents
CDKD-dependent activation of CDKA;1 controls microtubule dynamics and cytokinesis during meiosis
Kostika Sofroni, Hirotomo Takatsuka, Chao Yang, Nico Dissmeyer, Shinichiro Komaki, Yuki Hamamura, Lev Böttger, Masaaki Umeda, Arp Schnittger
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Article Pages: 1 Open access contents
Conserved metabolite regulation of stress granule assembly via AdoMet
Kyle Begovich, Anthony Q. Vu, Gene Yeo, James E. Wilhelm
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Article Pages: 1 Open access contents
Branched actin networks are assembled on microtubules by adenomatous polyposis coli for targeted membrane protrusion
Nadia Efimova, Changsong Yang, Jonathan X. Chia, Ning Li, Christopher J. Lengner, Kristi L. Neufeld, Tatyana M. Svitkina
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Article Pages: 1 Open access contents
A phase 1b study of dual PD-1 and CTLA-4 or KIR blockade in patients with relapsed/refractory lymphoid malignancies
Philippe Armand, Alexander Lesokhin, Ivan Borrello, John Timmerman, Martin Gutierrez, Lili Zhu, Mihaela Popa McKiver, Stephen M. Ansell
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Article Pages: 9 Open access contents
Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS
A. Kuendgen, M. Nomdedeu, H. Tuechler, G. Garcia-Manero, R. S. Komrokji, M. A. Sekeres, M. G. Della Porta, M. Cazzola, A. E. DeZern, G. J. Roboz, D. P. Steensma, A. A. Van de Loosdrecht, R. F. Schlenk, J. Grau, X. Calvo, S. Blum, A. Pereira, P. Valent, D. Costa, A. Giagounidis, B. Xicoy, H. Döhner, U. Platzbecker, C. Pedro, M. Lübbert, I. Oiartzabal, M. Díez-Campelo, M. T. Cedena, S. Machherndl-Spandl, M. López-Pavía, C. D. Baldus, M. Martinez-de-Sola, R. Stauder, B. Merchan, A. List, C. Ganster, T. Schroeder, M. T. Voso, M. Pfeilstöcker, H. Sill, B. Hildebrandt, J. Esteve, B. Nomdedeu, F. Cobo, R. Haas, F. Sole, U. Germing, P. L. Greenberg, D. Haase, G. Sanz
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Article Pages: 14 Open access contents
A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity
Wei Dong, Juan Lu, Xuejing Zhang, Yan Wu, Kaela Lettieri, Gerald R. Hammond, Yang Hong
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Article Pages: 1 Open access contents
Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia
Arnold Kloos, Konstantinos Mintzas, Lina Winckler, Razif Gabdoulline, Yasmine Alwie, Nidhi Jyotsana, Nadine Kattre, Renate Schottmann, Michaela Scherr, Charu Gupta, Felix F. Adams, Adrian Schwarzer, Dirk Heckl, Axel Schambach, Suzan Imren, R. Keith Humphries, Arnold Ganser, Felicitas Thol, Michael Heuser
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Article Pages: 12 Open access contents
SIX1 cooperates with RUNX1 and SMAD4 in cell fate commitment of Müllerian duct epithelium
Jumpei Terakawa, Vanida A. Serna, Devi M. Nair, Shigeru Sato, Kiyoshi Kawakami, Sally Radovick, Pascal Maire, Takeshi Kurita
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Article Pages: 13 Open access contents
Structural insight into the formation of lipoprotein-β-barrel complexes
Raquel Rodríguez-Alonso, Juliette Létoquart, Nguyen Van Son, Gwennaelle Louis, Antonio N. Calabrese, Bogdan I. Iorga, Sheena E. Radford, Seung-Hyun Cho, Han Remaut, Jean-François Collet
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Article Pages: 6 Open access contents