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Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans
Angelica Gualtieri, Nikolina Kyprianou, Louise C. Gregory, Maria Lillina Vignola, James G. Nicholson, Rachael Tan, Shin-ichi Inoue, Valeria Scagliotti, Pedro Casado, James Blackburn, Fernando Abollo-Jimenez, Eugenia Marinelli, Rachael E. J. Besser, Wolfgang Högler, I. Karen Temple, Justin H. Davies, Andrey Gagunashvili, Iain C.A.F. Robinson, Sally A. Camper, Shannon W. Davis, Pedro R. Cutillas, Evelien F. Gevers, Yoko Aoki, Mehul T. Dattani, Carles Gaston-Massuet
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
Kevin J. Selva, Carolien E. van de Sandt, Melissa M. Lemke, Christina Y. Lee, Suzanne K. Shoffner, Brendon Y. Chua, Samantha K. Davis, Thi H. O. Nguyen, Louise C. Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, Francesca Mordant, David C. Jackson, Katie L. Flanagan, Jane Crowe, Shidan Tosif, Melanie R. Neeland, Philip Sutton, Paul V. Licciardi, Nigel W. Crawford, Allen C. Cheng, Denise L. Doolan, Fatima Amanat, Florian Krammer, Keith Chappell, Naphak Modhiran, Daniel Watterson, Paul Young, Wen Shi Lee, Bruce D. Wines, P. Mark Hogarth, Robyn Esterbauer, Hannah G. Kelly, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Kelly B. Arnold, Katherine Kedzierska, Amy W. Chung
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
A reconciled solution of Meltwater Pulse 1A sources using sea-level fingerprinting
Yucheng Lin, Fiona D. Hibbert, Pippa L. Whitehouse, Sarah A. Woodroffe, Anthony Purcell, Ian Shennan, Sarah L. Bradley
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Network dynamics of hypothalamic feeding neurons
Patrick Sweeney, Can Chen, Indika Rajapakse, Roger D. Cone
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Hidden order and multipolar exchange striction in a correlated <i>f</i>-electron system
Leonid V. Pourovskii, Sergii Khmelevskyi
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Deep generative selection models of T and B cell receptor repertoires with soNNia
Giulio Isacchini, Aleksandra M. Walczak, Thierry Mora, Armita Nourmohammad
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Nanoanalytical analysis of bisphosphonate-driven alterations of microcalcifications using a 3D hydrogel system and in vivo mouse model
Jessica L. Ruiz, Joshua D. Hutcheson, Luis Cardoso, Amirala Bakhshian Nik, Alexandra Condado de Abreu, Tan Pham, Fabrizio Buffolo, Sara Busatto, Stefania Federici, Andrea Ridolfi, Masanori Aikawa, Sergio Bertazzo, Paolo Bergese, Sheldon Weinbaum, Elena Aikawa
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Using Hawkes Processes to model imported and local malaria cases in near-elimination settings
H. Juliette T. Unwin, Isobel Routledge, Seth Flaxman, Marian-Andrei Rizoiu, Shengjie Lai, Justin Cohen, Daniel J. Weiss, Swapnil Mishra, Samir Bhatt
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature
Camila Farias Amorim, Fernanda O. Novais, Ba T. Nguyen, Mauricio T. Nascimento, Jamile Lago, Alexsandro S. Lago, Lucas P. Carvalho, Daniel P. Beiting, Phillip Scott
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
LuxT controls specific quorum-sensing-regulated behaviors in <i>Vibrionaceae</i> spp. via repression of <i>qrr</i>1, encoding a small regulatory RNA
Michaela J. Eickhoff, Chenyi Fei, Xiuliang Huang, Bonnie L. Bassler
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Stress and odorant receptor feedback during a critical period after hatching regulates olfactory sensory neuron differentiation in <i>Drosophila</i>
Shadi Jafari, Johan Henriksson, Hua Yan, Mattias Alenius
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during <i>Pseudomonas aeruginosa</i> infection
Wanhai Qin, Xanthe Brands, Cornelis van’t Veer, Alex F. de Vos, Jean-Claude Sirard, Joris J. T. H. Roelofs, Brendon P. Scicluna, Tom van der Poll
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Individual differences in the perception of probability
Mel W. Khaw, Luminita Stevens, Michael Woodford
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease
Marta Vergnano, Maja Mockenhaupt, Natashia Benzian-Olsson, Maren Paulmann, Katarzyna Grys, Satveer K. Mahil, Charlotte Chaloner, Ines A. Barbosa, A. David Burden, Siew-Eng Choon, Alex A. Navarini, Nick J. Reynolds, Richard B. Warren, Thamir Abraham, Mahmud Ali, Suzannah August, David Baudry, Anthony Bewley, Hywel Cooper, Christopher E.M. Griffiths, John Ingram, Susan Kelly, Mohsen Korshid, Effie Ladoyanni, John McKenna, Freya Meynell, Richard Parslew, Prakash Patel, Angela Pushparajah, Nick Reynolds, Catherine Smith, Shyamal Wahie, Richard Warren, Andrew Wright, Ulrike Huffmeier, Patrick Baum, Sudha Visvanathan, Jonathan N. Barker, Catherine H. Smith, Francesca Capon
Publication Date: 01 April, 2021
Article Pages: 1 Open access contents
Opportunities and challenges for the computational interpretation of rare variation in clinically important genes
Gregory McInnes, Andrew G. Sharo, Megan L. Koleske, Julia E.H. Brown, Matthew Norstad, Aashish N. Adhikari, Sheng Wang, Steven E. Brenner, Jodi Halpern, Barbara A. Koenig, David C. Magnus, Renata C. Gallagher, Kathleen M. Giacomini, Russ B. Altman
Publication Date: 01 April, 2021
Article Pages: 13 Open access contents
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