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APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
Tung-Chang Liu, Chun-Ting Lin, Kai-Cheng Chang, Kai-Wei Guo, Shuying Wang, Jhih-Wei Chu, Yu-Yuan Hsiao
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Article Pages: 1 Open access contents
Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
Yibin Liu, Zhiyuan Hu, Jingfei Cheng, Paulina Siejka-Zielińska, Jinfeng Chen, Masato Inoue, Ahmed Ashour Ahmed, Chun-Xiao Song
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Article Pages: 1 Open access contents
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
Run Jin, Samantha Klasfeld, Yang Zhu, Meilin Fernandez Garcia, Jun Xiao, Soon-Ki Han, Adam Konkol, Doris Wagner
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Article Pages: 1 Open access contents
TALEN outperforms Cas9 in editing heterochromatin target sites
Surbhi Jain, Saurabh Shukla, Che Yang, Meng Zhang, Zia Fatma, Manasi Lingamaneni, Shireen Abesteh, Stephan Thomas Lane, Xiong Xiong, Yuchuan Wang, Charles M. Schroeder, Paul R. Selvin, Huimin Zhao
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Article Pages: 1 Open access contents
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics
Monica C. Pillon, Meredith N. Frazier, Lucas B. Dillard, Jason G. Williams, Seda Kocaman, Juno M. Krahn, Lalith Perera, Cassandra K. Hayne, Jacob Gordon, Zachary D. Stewart, Mack Sobhany, Leesa J. Deterding, Allen L. Hsu, Venkata P. Dandey, Mario J. Borgnia, Robin E. Stanley
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Article Pages: 1 Open access contents
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
Fatima Rizvi, Elissa Everton, Anna R. Smith, Hua Liu, Elizabeth Osota, Mitchell Beattie, Ying Tam, Norbert Pardi, Drew Weissman, Valerie Gouon-Evans
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Article Pages: 1 Open access contents
A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice
Ting Li, Xianjun Chen, Yajie Qian, Jiawei Shao, Xie Li, Shuning Liu, Linyong Zhu, Yuzheng Zhao, Haifeng Ye, Yi Yang
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Article Pages: 1 Open access contents
A CD8<sup>+</sup> NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis
Eoin F. McKinney, Iona Cuthbertson, Kristina M. Harris, Dawn E. Smilek, Christopher Connor, Giulia Manferrari, Edward J. Carr, Scott S. Zamvil, Kenneth G. C. Smith
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Article Pages: 1 Open access contents
Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
Dongtak Lee, Dongsung Park, Insu Kim, Sang Won Lee, Wonseok Lee, Kyo Seon Hwang, Jeong Hoon Lee, Gyudo Lee, Dae Sung Yoon
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Article Pages: 1 Open access contents
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
Simon Renders, Arthur Flohr Svendsen, Jasper Panten, Nicolas Rama, Maria Maryanovich, Pia Sommerkamp, Luisa Ladel, Anna Rita Redavid, Benjamin Gibert, Seka Lazare, Benjamin Ducarouge, Katharina Schönberger, Andreas Narr, Manon Tourbez, Bertien Dethmers-Ausema, Erik Zwart, Agnes Hotz-Wagenblatt, Dachuan Zhang, Claudia Korn, Petra Zeisberger, Adriana Przybylla, Markus Sohn, Simon Mendez-Ferrer, Mathias Heikenwälder, Maik Brune, Daniel Klimmeck, Leonid Bystrykh, Paul S. Frenette, Patrick Mehlen, Gerald de Haan, Nina Cabezas-Wallscheid, Andreas Trumpp
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Article Pages: 1 Open access contents