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Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Tsan-Wen Lu, Phillip C. Aoto, Jui-Hung Weng, Cole Nielsen, Jennifer N. Cash, James Hall, Ping Zhang, Sanford M. Simon, Michael A. Cianfrocco, Susan S. Taylor
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Article Pages: 1 Open access contents
Super-resolution visualization of distinct stalled and broken replication fork structures
Donna R. Whelan, Wei Ting C. Lee, Frances Marks, Yu Tina Kong, Yandong Yin, Eli Rothenberg
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Article Pages: 1 Open access contents
Signatures of host–pathogen evolutionary conflict reveal MISTR—A conserved <span style="text-decoration: underline">MI</span>tochondrial <span style="text-decoration: underline">ST</span>ress <span style="text-decoration: underline">R</span>esponse network
Mahsa Sorouri, Tyron Chang, Palmy Jesudhasan, Chelsea Pinkham, Nels C. Elde, Dustin C. Hancks
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Article Pages: 1 Open access contents
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density
Anna L. Swan, Christine Schütt, Jan Rozman, Maria del Mar Muñiz Moreno, Stefan Brandmaier, Michelle Simon, Stefanie Leuchtenberger, Mark Griffiths, Robert Brommage, Piia Keskivali-Bond, Harald Grallert, Thomas Werner, Raffaele Teperino, Lore Becker, Gregor Miller, Ala Moshiri, John R. Seavitt, Derek D. Cissell, Terrence F. Meehan, Elif F. Acar, Christopher J. Lelliott, Ann M. Flenniken, Marie-France Champy, Tania Sorg, Abdel Ayadi, Robert E. Braun, Heather Cater, Mary E. Dickinson, Paul Flicek, Juan Gallegos, Elena J. Ghirardello, Jason D. Heaney, Sylvie Jacquot, Connor Lally, John G. Logan, Lydia Teboul, Jeremy Mason, Nadine Spielmann, Colin McKerlie, Stephen A. Murray, Lauryl M. J. Nutter, Kristian F. Odfalk, Helen Parkinson, Jan Prochazka, Corey L. Reynolds, Mohammed Selloum, Frantisek Spoutil, Karen L. Svenson, Taylor S. Vales, Sara E. Wells, Jacqueline K. White, Radislav Sedlacek, Wolfgang Wurst, K. C. Kent Lloyd, Peter I. Croucher, Helmut Fuchs, Graham R. Williams, J. H. Duncan Bassett, Valerie Gailus-Durner, Yann Herault, Ann-Marie Mallon, Steve D. M. Brown, Philipp Mayer-Kuckuk, Martin Hrabe de Angelis
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Article Pages: 1 Open access contents
Increased prostaglandin-D<sub>2</sub> in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation
Elisabeth Stelling, Melanie Ricke-Hoch, Sergej Erschow, Steve Hoffmann, Anke Katharina Bergmann, Maren Heimerl, Stefan Pietzsch, Karin Battmer, Alexandra Haase, Britta Stapel, Michaela Scherr, Jean-Luc Balligand, Ofer Binah, Denise Hilfiker-Kleiner
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Article Pages: 1 Open access contents
Deficiency of mannose-binding lectin is a risk of <i>Pneumocystis jirovecii</i> pneumonia in a natural history cohort of people living with HIV/AIDS in Northern Thailand
Kunio Yanagisawa, Nuanjun Wichukchinda, Naho Tsuchiya, Michio Yasunami, Archawin Rojanawiwat, Hidenori Tanaka, Hiroh Saji, Yoshiyuki Ogawa, Hiroshi Handa, Panita Pathipvanich, Koya Ariyoshi, Pathom Sawanpanyalert
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Article Pages: 1 Open access contents
Polymorphisms in mitochondrial ribosomal protein S5 (<i>MRPS5</i>) are associated with leprosy risk in Chinese
Yan Xing, Jun He, Yan Wen, Jian Liu, Yuangang You, Xiaoman Weng, Lianchao Yuan, Li Xiong, Xiaohua Chen, Ying Zhang, Huan-Ying Li
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Article Pages: 1 Open access contents
Genomic and morphological evidence of distinct populations in the endemic common (weedy) seadragon <i>Phyllopteryx taeniolatus</i> (Syngnathidae) along the east coast of Australia
O. Selma Klanten, Michelle R. Gaither, Samuel Greaves, Kade Mills, Kristine O’Keeffe, John Turnbull, Rob McKinnon, David J. Booth
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Article Pages: 1 Open access contents
Identification of chironomid species as natural reservoirs of toxigenic <i>Vibrio cholerae</i> strains with pandemic potential
Sivan Laviad-Shitrit, Rotem Sela, Leena Thorat, Yehonatan Sharaby, Ido Izhaki, Bimalendu B. Nath, Malka Halpern
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Article Pages: 1 Open access contents
Biparental contributions of the <i>H2A</i>.<i>B</i> histone variant control embryonic development in mice
Antoine Molaro, Anna J. Wood, Derek Janssens, Selina M. Kindelay, Michael T. Eickbush, Steven Wu, Priti Singh, Charles H. Muller, Steven Henikoff, Harmit S. Malik
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Article Pages: 1 Open access contents