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Immune cells fold and damage fungal hyphae
Judith M. Bain, M. Fernanda Alonso, Delma S. Childers, Catriona A. Walls, Kevin Mackenzie, Arnab Pradhan, Leanne E. Lewis, Johanna Louw, Gabriela M. Avelar, Daniel E. Larcombe, Mihai G. Netea, Neil A. R. Gow, Gordon D. Brown, Lars P. Erwig, Alistair J. P. Brown
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Article Pages: 1 Open access contents
Signatures of immune dysfunction in HIV and HCV infection share features with chronic inflammation in aging and persist after viral reduction or elimination
Cesar J. Lopez Angel, Edward A. Pham, Huixun Du, Francesco Vallania, Benjamin J. Fram, Kevin Perez, Thai Nguyen, Yael Rosenberg-Hasson, Aijaz Ahmed, Cornelia L. Dekker, Philip M. Grant, Purvesh Khatri, Holden T. Maecker, Jeffrey S. Glenn, Mark M. Davis, David Furman
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Article Pages: 1 Open access contents
CD11c<sup>+</sup>CD88<sup>+</sup>CD317<sup>+</sup> myeloid cells are critical mediators of persistent CNS autoimmunity
Navid Manouchehri, Rehana Z. Hussain, Petra D. Cravens, Ekaterina Esaulova, Maxim N. Artyomov, Brian T. Edelson, Gregory F. Wu, Anne H. Cross, Richard Doelger, Nicolas Loof, Todd N. Eagar, Thomas G. Forsthuber, Laurent Calvier, Joachim Herz, Olaf Stüve
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Article Pages: 1 Open access contents
TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections
Seoyun Yum, Minghao Li, Yan Fang, Zhijian J. Chen
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Article Pages: 1 Open access contents
Gain-of-function factor H–related 5 protein impairs glomerular complement regulation resulting in kidney damage
Talat H. Malik, Daniel P. Gitterman, Deborah P. Lavin, Hannah J. Lomax-Browne, E. Christina Hiemeyer, Linda B. Moran, Katharina Boroviak, H. Terence Cook, Alyssa C. Gilmore, Mawj Mandwie, Amina Ahmad, Ian E. Alexander, Grant J. Logan, Kevin J. Marchbank, Allan Bradley, Matthew C. Pickering
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Article Pages: 1 Open access contents
Mitochondrial metabolism is essential for invariant natural killer T cell development and function
Xiufang Weng, Amrendra Kumar, Liang Cao, Ying He, Eva Morgun, Lavanya Visvabharathy, Jie Zhao, Laura A. Sena, Sam E. Weinberg, Navdeep S. Chandel, Chyung-Ru Wang
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Article Pages: 1 Open access contents
Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis
Dana L. E. Vergoossen, Jaap J. Plomp, Christoph Gstöttner, Yvonne E. Fillié-Grijpma, Roy Augustinus, Robyn Verpalen, Manfred Wuhrer, Paul W. H. I. Parren, Elena Dominguez-Vega, Silvère M. van der Maarel, Jan J. Verschuuren, Maartje G. Huijbers
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Article Pages: 1 Open access contents
Sema7A is crucial for resolution of severe inflammation
Andreas Körner, Alice Bernard, Julia C. Fitzgerald, Juan Carlos Alarcon-Barrera, Sarantos Kostidis, Torsten Kaussen, Martin Giera, Valbona Mirakaj
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Article Pages: 1 Open access contents
T cells selectively filter oscillatory signals on the minutes timescale
Geoff P. O’Donoghue, Lukasz J. Bugaj, Warren Anderson, Kyle G. Daniels, David J. Rawlings, Wendell A. Lim
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Article Pages: 1 Open access contents
Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches
Hwai Wen Chang, Gerhard Frey, Haizhen Liu, Charles Xing, Lawrence Steinman, William J. Boyle, Jay M. Short
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Article Pages: 1 Open access contents