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KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
Timothy H. Tran, Albert H. Chan, Lucy C. Young, Lakshman Bindu, Chris Neale, Simon Messing, Srisathiyanarayanan Dharmaiah, Troy Taylor, John-Paul Denson, Dominic Esposito, Dwight V. Nissley, Andrew G. Stephen, Frank McCormick, Dhirendra K. Simanshu
Publication Date: 19 February, 2021
Article Pages: 1 Open access contents
Crystal structure of a photosynthetic LH1-RC in complex with its electron donor HiPIP
Tomoaki Kawakami, Long-Jiang Yu, Tai Liang, Koudai Okazaki, Michael T. Madigan, Yukihiro Kimura, Zheng-Yu Wang-Otomo
Publication Date: 17 February, 2021
Article Pages: 1 Open access contents
Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against <i>P. falciparum</i>
Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Gonzalo Gonzalez-Paez, Zhen Han, Katherine L. Williams, Wayne Volkmuth, Daniel Emerling, Emily Locke, C. Richter King, Fidel Zavala, Ian A. Wilson
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones
Fa-Hui Sun, Peng Zhao, Nan Zhang, Lu-Lu Kong, Catherine C. L. Wong, Cai-Hong Yun
Publication Date: 15 February, 2021
Article Pages: 1 Open access contents
Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase
Leo Bellin, Francisco Del Caño-Ochoa, Adrián Velázquez-Campoy, Torsten Möhlmann, Santiago Ramón-Maiques
Publication Date: 11 February, 2021
Article Pages: 1 Open access contents
Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation
Yongming Du, Yinxia Yan, Si Xie, Hao Huang, Xin Wang, Ray Kit Ng, Ming-Ming Zhou, Chengmin Qian
Publication Date: 11 February, 2021
Article Pages: 1 Open access contents
Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor
Toshinori Oozeki, Tadashi Nakai, Kazuki Kozakai, Kazuki Okamoto, Shun’ichi Kuroda, Kazuo Kobayashi, Katsuyuki Tanizawa, Toshihide Okajima
Publication Date: 10 February, 2021
Article Pages: 1 Open access contents
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
Jason C. Klima, Lindsey A. Doyle, Justin Daho Lee, Michael Rappleye, Lauren A. Gagnon, Min Yen Lee, Emilia P. Barros, Anastassia A. Vorobieva, Jiayi Dou, Samantha Bremner, Jacob S. Quon, Cameron M. Chow, Lauren Carter, David L. Mack, Rommie E. Amaro, Joshua C. Vaughan, Andre Berndt, Barry L. Stoddard, David Baker
Publication Date: 08 February, 2021
Article Pages: 1 Open access contents
Discovery of an ene-reductase for initiating flavone and flavonol catabolism in gut bacteria
Gaohua Yang, Sen Hong, Pengjie Yang, Yuwei Sun, Yong Wang, Peng Zhang, Weihong Jiang, Yang Gu
Publication Date: 04 February, 2021
Article Pages: 1 Open access contents
The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases
Janne J. Mäkinen, Yeonoh Shin, Eeva Vieras, Pasi Virta, Mikko Metsä-Ketelä, Katsuhiko S. Murakami, Georgiy A. Belogurov
Publication Date: 04 February, 2021
Article Pages: 1 Open access contents