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Local computational methods to improve the interpretability and analysis of cryo-EM maps
Satinder Kaur, Josue Gomez-Blanco, Ahmad A. Z. Khalifa, Swathi Adinarayanan, Ruben Sanchez-Garcia, Daniel Wrapp, Jason S. McLellan, Khanh Huy Bui, Javier Vargas
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Article Pages: 1 Open access contents
Transcription activation by a sliding clamp
Jing Shi, Aijia Wen, Sha Jin, Bo Gao, Yang Huang, Yu Feng
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Article Pages: 1 Open access contents
Eltrombopag directly inhibits BAX and prevents cell death
Adam Z. Spitz, Emmanouil Zacharioudakis, Denis E. Reyna, Thomas P. Garner, Evripidis Gavathiotis
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Article Pages: 1 Open access contents
Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis
Lynn Radamaker, Julian Baur, Stefanie Huhn, Christian Haupt, Ute Hegenbart, Stefan Schönland, Akanksha Bansal, Matthias Schmidt, Marcus Fändrich
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Article Pages: 1 Open access contents
Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes
Sabine Wittig, Marcelo Ganzella, Marie Barth, Susann Kostmann, Dietmar Riedel, Ángel Pérez-Lara, Reinhard Jahn, Carla Schmidt
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Article Pages: 1 Open access contents
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate
Joanna L. Fox, Michelle A. Hughes, Xin Meng, Nikola A. Sarnowska, Ian R. Powley, Rebekah Jukes-Jones, David Dinsdale, Timothy J. Ragan, Louise Fairall, John W. R. Schwabe, Nobuhiro Morone, Kelvin Cain, Marion MacFarlane
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Article Pages: 1 Open access contents
Cryo-EM of mammalian PA28αβ-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28αβ
Jinhuan Chen, Yifan Wang, Cong Xu, Kaijian Chen, Qiaoyu Zhao, Shutian Wang, Yue Yin, Chao Peng, Zhanyu Ding, Yao Cong
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Article Pages: 1 Open access contents
Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification
Corey H. Yu, Akash Bhattacharya, Mirjana Persaud, Alexander B. Taylor, Zhonghua Wang, Angel Bulnes-Ramos, Joella Xu, Anastasia Selyutina, Alicia Martinez-Lopez, Kristin Cano, Borries Demeler, Baek Kim, Stephen C. Hardies, Felipe Diaz-Griffero, Dmitri N. Ivanov
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Article Pages: 1 Open access contents
Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP
Katerina Naydenova, Kyle W. Muir, Long-Fei Wu, Ziguo Zhang, Francesca Coscia, Mathew J. Peet, Pablo Castro-Hartmann, Pu Qian, Kasim Sader, Kyle Dent, Dari Kimanius, John D. Sutherland, Jan Löwe, David Barford, Christopher J. Russo
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Article Pages: 1 Open access contents
Backbone-independent NMR resonance assignments of methyl probes in large proteins
Santrupti Nerli, Viviane S. De Paula, Andrew C. McShan, Nikolaos G. Sgourakis
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Article Pages: 1 Open access contents