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Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Zhiyong Wang, Yusuke Goto, Michael M. Allevato, Victoria H. Wu, Robert Saddawi-Konefka, Mara Gilardi, Diego Alvarado, Bryan S. Yung, Aoife O’Farrell, Alfredo A. Molinolo, Umamaheswar Duvvuri, Jennifer R. Grandis, Joseph A. Califano, Ezra E. W. Cohen, J. Silvio Gutkind

Publication Date: 2021-04-22T00:00

Article Pages: 1

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Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells

Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells

Rebekka Duhen, Carmen Ballesteros-Merino, Alexandra K. Frye, Eric Tran, Venkatesh Rajamanickam, Shu-Ching Chang, Yoshinobu Koguchi, Carlo B. Bifulco, Brady Bernard, Rom S. Leidner, Brendan D. Curti, Bernard A. Fox, Walter J. Urba, R. Bryan Bell, Andrew D. Weinberg

Publication Date: 2021-02-16T00:00

Article Pages: 1

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