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The long non-coding RNA <i>MIR31HG</i> regulates the senescence associated secretory phenotype
Marta Montes, Michal Lubas, Frederic S. Arendrup, Bettina Mentz, Neha Rohatgi, Sarunas Tumas, Lea M. Harder, Anders J. Skanderup, Jens S. Andersen, Anders H. Lund
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Article Pages: 1 Open access contents
Autophagy of the m<sup>6</sup>A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis
Yan-Hong Cui, Seungwon Yang, Jiangbo Wei, Christopher R. Shea, Wen Zhong, Fang Wang, Palak Shah, Muhammad G. Kibriya, Xiaolong Cui, Habibul Ahsan, Chuan He, Yu-Ying He
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Article Pages: 1 Open access contents
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability
Zsuzsanna Nagy, Janith A. Seneviratne, Maxwell Kanikevich, William Chang, Chelsea Mayoh, Pooja Venkat, Yanhua Du, Cizhong Jiang, Alice Salib, Jessica Koach, Daniel R. Carter, Rituparna Mittra, Tao Liu, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
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Article Pages: 1 Open access contents
KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
Timothy H. Tran, Albert H. Chan, Lucy C. Young, Lakshman Bindu, Chris Neale, Simon Messing, Srisathiyanarayanan Dharmaiah, Troy Taylor, John-Paul Denson, Dominic Esposito, Dwight V. Nissley, Andrew G. Stephen, Frank McCormick, Dhirendra K. Simanshu
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Article Pages: 1 Open access contents
RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia
Vasily V. Grinev, Farnaz Barneh, Ilya M. Ilyushonak, Sirintra Nakjang, Job Smink, Anita van Oort, Richard Clough, Michael Seyani, Hesta McNeill, Mojgan Reza, Natalia Martinez-Soria, Salam A. Assi, Tatsiana V. Ramanouskaya, Constanze Bonifer, Olaf Heidenreich
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Article Pages: 1 Open access contents
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
Silvia Pomella, Prethish Sreenivas, Berkley E. Gryder, Long Wang, David Milewski, Matteo Cassandri, Kunal Baxi, Nicole R. Hensch, Elena Carcarino, Young Song, Hsien-Chao Chou, Marielle E. Yohe, Benjamin Z. Stanton, Bruno Amadio, Ignazio Caruana, Cristiano De Stefanis, Rita De Vito, Franco Locatelli, Yidong Chen, Eleanor Y. Chen, Peter Houghton, Javed Khan, Rossella Rota, Myron S. Ignatius
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Article Pages: 1 Open access contents
Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress
Katharine J. Herbert, Rathi Puliyadi, Remko Prevo, Gonzalo Rodriguez-Berriguete, Anderson Ryan, Kristijan Ramadan, Geoff S. Higgins
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Article Pages: 13 Open access contents
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation
Yina Liao, Yijun Hua, Yizhuo Li, Changlin Zhang, Wendan Yu, Ping Guo, Kun Zou, Wenyang Li, Yao Sun, Ruozhu Wang, Yan Zuo, Silei Sui, Chunfang Tian, Jiaojiao Hao, Manyu Chen, Sheng Hu, Miao Chen, Qian Long, Xiaonan Wang, Lijuan Zou, Fangyun Xie, Wei Guo, Wuguo Deng
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Article Pages: 16 Open access contents
Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment
Chenfei Zhou, Yanmei Zhang, Ruiming Yan, Lei Huang, Andrew L. Mellor, Yang Yang, Xiaojing Chen, Wenfei Wei, Xiangguang Wu, Lan Yu, Luojiao Liang, Dan Zhang, Sha Wu, Wei Wang
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Article Pages: 14 Open access contents
TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα
Jianxiong Ji, Kaikai Ding, Tao Luo, Xin Zhang, Anjing Chen, Di Zhang, Gang Li, Frits Thorsen, Bin Huang, Xingang Li, Jian Wang
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Article Pages: 14 Open access contents