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Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon
Atsuo Nakamura, Shin Kurihara, Daisuke Takahashi, Wakana Ohashi, Yutaka Nakamura, Shunsuke Kimura, Masayoshi Onuki, Aiko Kume, Yukiko Sasazawa, Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda, Shinji Saiki, Mitsuharu Matsumoto, Koji Hase
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Article Pages: 1 Open access contents
Single-cell analyses of Crohn’s disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions
Natalia Jaeger, Ramya Gamini, Marina Cella, Jorge L. Schettini, Mattia Bugatti, Shanrong Zhao, Charles V. Rosadini, Ekaterina Esaulova, Blanda Di Luccia, Baylee Kinnett, William Vermi, Maxim N. Artyomov, Thomas A. Wynn, Ramnik J. Xavier, Scott A. Jelinsky, Marco Colonna
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Article Pages: 1 Open access contents
SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition
Peter J. Mullen, Gustavo Garcia, Arunima Purkayastha, Nedas Matulionis, Ernst W. Schmid, Milica Momcilovic, Chandani Sen, Justin Langerman, Arunachalam Ramaiah, David B. Shackelford, Robert Damoiseaux, Samuel W. French, Kathrin Plath, Brigitte N. Gomperts, Vaithilingaraja Arumugaswami, Heather R. Christofk
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Article Pages: 1 Open access contents
Lysates of <i>Methylococcus capsulatus</i> Bath induce a lean-like microbiota, intestinal FoxP3<sup>+</sup>RORγt<sup>+</sup>IL-17<sup>+</sup> Tregs and improve metabolism
Benjamin A. H. Jensen, Jacob B. Holm, Ida S. Larsen, Nicole von Burg, Stefanie Derer, Si B. Sonne, Simone I. Pærregaard, Mads V. Damgaard, Stine A. Indrelid, Aymeric Rivollier, Anne-Laure Agrinier, Karolina Sulek, Yke J. Arnoldussen, Even Fjære, André Marette, Inga L. Angell, Knut Rudi, Jonas T. Treebak, Lise Madsen, Caroline Piercey Åkesson, William Agace, Christian Sina, Charlotte R. Kleiveland, Karsten Kristiansen, Tor E. Lea
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Article Pages: 1 Open access contents
Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation
Yosuke Kurashima, Takaaki Kigoshi, Sayuri Murasaki, Fujimi Arai, Kaoru Shimada, Natsumi Seki, Yun-Gi Kim, Koji Hase, Hiroshi Ohno, Kazuya Kawano, Hiroshi Ashida, Toshihiko Suzuki, Masako Morimoto, Yukari Saito, Ai Sasou, Yuki Goda, Yoshikazu Yuki, Yutaka Inagaki, Hideki Iijima, Wataru Suda, Masahira Hattori, Hiroshi Kiyono
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Article Pages: 1 Open access contents
Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis
Peng Lu, Yukihiro Yamaguchi, William B. Fulton, Sanxia Wang, Qinjie Zhou, Hongpeng Jia, Mark L. Kovler, Andres Gonzalez Salazar, Maame Sampah, Thomas Prindle, Peter Wipf, Chhinder P. Sodhi, David J. Hackam
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Article Pages: 1 Open access contents
Host immunity modulates the efficacy of microbiota transplantation for treatment of <i>Clostridioides difficile</i> infection
Eric R. Littmann, Jung-Jin Lee, Joshua E. Denny, Zahidul Alam, Jeffrey R. Maslanka, Isma Zarin, Rina Matsuda, Rebecca A. Carter, Bože Susac, Miriam S. Saffern, Bryton Fett, Lisa M. Mattei, Kyle Bittinger, Michael C. Abt
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Article Pages: 1 Open access contents
Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes
Daniel R. Monaco, Brandon M. Sie, Thomas R. Nirschl, Audrey C. Knight, Hugh A. Sampson, Anna Nowak-Wegrzyn, Robert A. Wood, Robert G. Hamilton, Pamela A. Frischmeyer-Guerrerio, H. Benjamin Larman
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Article Pages: 1 Open access contents
NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn’s disease
Nicolas Rochereau, Xavier Roblin, Eva Michaud, Rémi Gayet, Blandine Chanut, Fabienne Jospin, Blaise Corthésy, Stéphane Paul
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Article Pages: 1 Open access contents