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A data-independent acquisition-based global phosphoproteomics system enables deep profiling
Reta Birhanu Kitata, Wai-Kok Choong, Chia-Feng Tsai, Pei-Yi Lin, Bo-Shiun Chen, Yun-Chien Chang, Alexey I. Nesvizhskii, Ting-Yi Sung, Yu-Ju Chen
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Article Pages: 1 Open access contents
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures
Giulia Franciosa, Jos G. A. Smits, Sonia Minuzzo, Ana Martinez-Val, Stefano Indraccolo, Jesper V. Olsen
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Article Pages: 1 Open access contents
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
Omar M. Khan, Jorge Almagro, Jessica K. Nelson, Stuart Horswell, Vesela Encheva, Kripa S. Keyan, Bruce E. Clurman, Ambrosius P. Snijders, Axel Behrens
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Article Pages: 1 Open access contents
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry
N. Tavernier, Y. Thomas, S. Vigneron, P. Maisonneuve, S. Orlicky, P. Mader, S. G. Regmi, L. Van Hove, N. M. Levinson, G. Gasmi-Seabrook, N. Joly, M. Poteau, G. Velez-Aguilera, O. Gavet, A. Castro, M. Dasso, T. Lorca, F. Sicheri, L. Pintard
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Article Pages: 1 Open access contents
System-wide identification and prioritization of enzyme substrates by thermal analysis
Amir Ata Saei, Christian M. Beusch, Pierre Sabatier, Juan Astorga Wells, Hassan Gharibi, Zhaowei Meng, Alexey Chernobrovkin, Sergey Rodin, Katja Näreoja, Ann-Gerd Thorsell, Tobias Karlberg, Qing Cheng, Susanna L. Lundström, Massimiliano Gaetani, Ákos Végvári, Elias S. J. Arnér, Herwig Schüler, Roman A. Zubarev
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Article Pages: 1 Open access contents
Deep learning the collisional cross sections of the peptide universe from a million experimental values
Florian Meier, Niklas D. Köhler, Andreas-David Brunner, Jean-Marc H. Wanka, Eugenia Voytik, Maximilian T. Strauss, Fabian J. Theis, Matthias Mann
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Article Pages: 1 Open access contents
Tuning the H‐Atom Transfer Reactivity of Iron(IV)‐Oxo Complexes as Probed by Infrared Photodissociation Spectroscopy
Guilherme L. Tripodi, Magda M. J. Dekker, Jana Roithová, Lawrence Que
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Article Pages: 5 Open access contents
Mechanism of the small ATP-independent chaperone Spy is substrate specific
Rishav Mitra, Varun V. Gadkari, Ben A. Meinen, Carlo P. M. van Mierlo, Brandon T. Ruotolo, James C. A. Bardwell
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Article Pages: 1 Open access contents
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF
David McMillan, Carlos Martinez-Fleites, John Porter, David Fox, Rachel Davis, Prashant Mori, Tom Ceska, Bruce Carrington, Alastair Lawson, Tim Bourne, James O’Connell
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Article Pages: 1 Open access contents
Urinary proteome profiling for stratifying patients with familial Parkinson’s disease
Sebastian Virreira Winter, Ozge Karayel, Maximilian T Strauss, Shalini Padmanabhan, Matthew Surface, Kalpana Merchant, Roy N Alcalay, Matthias Mann
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Article Pages: 1 Open access contents