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Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
Zhen Miao, Michael S. Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamas Aranyi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H. Kaestner, Katalin Susztak
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Article Pages: 1 Open access contents
Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling
Hao Huang, Jianyang Hu, Alishba Maryam, Qinghua Huang, Yuchen Zhang, Saravanan Ramakrishnan, Jingyu Li, Haiying Ma, Victor W. S. Ma, Wah Cheuk, Grace Y. K. So, Wei Wang, William C. S. Cho, Liang Zhang, Kui Ming Chan, Xin Wang, Y. Rebecca Chin
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Article Pages: 1 Open access contents
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
Yoshiharu Muto, Parker C. Wilson, Nicolas Ledru, Haojia Wu, Henrik Dimke, Sushrut S. Waikar, Benjamin D. Humphreys
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Article Pages: 1 Open access contents
An ancient, conserved gene regulatory network led to the rise of oral venom systems
Agneesh Barua, Alexander S. Mikheyev
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Article Pages: 1 Open access contents
A rationally engineered decoder of transient intracellular signals
Claude Lormeau, Fabian Rudolf, Jörg Stelling
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Article Pages: 1 Open access contents
Causal network models of SARS-CoV-2 expression and aging to identify candidates for drug repurposing
Anastasiya Belyaeva, Louis Cammarata, Adityanarayanan Radhakrishnan, Chandler Squires, Karren Dai Yang, G. V. Shivashankar, Caroline Uhler
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Article Pages: 1 Open access contents
LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
Luca Ducoli, Saumya Agrawal, Eliane Sibler, Tsukasa Kouno, Carlotta Tacconi, Chung-Chao Hon, Simone D. Berger, Daniela Müllhaupt, Yuliang He, Jihye Kim, Marco D’Addio, Lothar C. Dieterich, Piero Carninci, Michiel J. L. de Hoon, Jay W. Shin, Michael Detmar
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Article Pages: 1 Open access contents
RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia
Vasily V. Grinev, Farnaz Barneh, Ilya M. Ilyushonak, Sirintra Nakjang, Job Smink, Anita van Oort, Richard Clough, Michael Seyani, Hesta McNeill, Mojgan Reza, Natalia Martinez-Soria, Salam A. Assi, Tatsiana V. Ramanouskaya, Constanze Bonifer, Olaf Heidenreich
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Article Pages: 1 Open access contents
Cellular Heterogeneity–Adjusted cLonal Methylation (CHALM) improves prediction of gene expression
Jianfeng Xu, Jiejun Shi, Xiaodong Cui, Ya Cui, Jingyi Jessica Li, Ajay Goel, Xi Chen, Jean-Pierre Issa, Jianzhong Su, Wei Li
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Article Pages: 1 Open access contents
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis
Chia-Lung Wu, Amanda Dicks, Nancy Steward, Ruhang Tang, Dakota B. Katz, Yun-Rak Choi, Farshid Guilak
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Article Pages: 1 Open access contents