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Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation
Roser Vilarrasa-Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Marta Kulis, Xabier Agirre, Felipe Prosper, Renée Beekman, Silvia Beà, Dolors Colomer, Hendrik G. Stunnenberg, Ivo Gut, Elias Campo, Marc A. Marti-Renom, José Ignacio Martin-Subero
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Article Pages: 1 Open access contents
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
Run Jin, Samantha Klasfeld, Yang Zhu, Meilin Fernandez Garcia, Jun Xiao, Soon-Ki Han, Adam Konkol, Doris Wagner
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Article Pages: 1 Open access contents
Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals
Azad Alizada, Nadiya Khyzha, Liangxi Wang, Lina Antounians, Xiaoting Chen, Melvin Khor, Minggao Liang, Kumaragurubaran Rathnakumar, Matthew T. Weirauch, Alejandra Medina-Rivera, Jason E. Fish, Michael D. Wilson
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Article Pages: 1 Open access contents
Nanobody-mediated control of gene expression and epigenetic memory
Mike V. Van, Taihei Fujimori, Lacramioara Bintu
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Article Pages: 1 Open access contents
High-resolution targeted 3C interrogation of <i>cis</i>-regulatory element organization at genome-wide scale
Damien J. Downes, Robert A. Beagrie, Matthew E. Gosden, Jelena Telenius, Stephanie J. Carpenter, Lea Nussbaum, Sara De Ornellas, Martin Sergeant, Chris Q. Eijsbouts, Ron Schwessinger, Jon Kerry, Nigel Roberts, Arun Shivalingam, Afaf El-Sagheer, A. Marieke Oudelaar, Tom Brown, Veronica J. Buckle, James O. J. Davies, Jim R. Hughes
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Article Pages: 1 Open access contents
Large organized chromatin lysine domains help distinguish primitive from differentiated cell populations
Seyed Ali Madani Tonekaboni, Benjamin Haibe-Kains, Mathieu Lupien
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Article Pages: 1 Open access contents
Dissection of the <i>Fgf8</i> regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy
A. Hörnblad, S. Bastide, K. Langenfeld, F. Langa, F. Spitz
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Article Pages: 1 Open access contents
Dual RNA 3’-end processing of H2A.X messenger RNA maintains DNA damage repair throughout the cell cycle
Esther Griesbach, Margarita Schlackow, William F. Marzluff, Nick J. Proudfoot
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Article Pages: 1 Open access contents
Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems
Timothy C. Yu, Winnie L. Liu, Marcia S. Brinck, Jessica E. Davis, Jeremy Shek, Grace Bower, Tal Einav, Kimberly D. Insigne, Rob Phillips, Sriram Kosuri, Guillaume Urtecho
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Article Pages: 1 Open access contents
Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes
Tianxiong Yu, Kaili Fan, Deniz M. Özata, Gen Zhang, Yu Fu, William E. Theurkauf, Phillip D. Zamore, Zhiping Weng
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Article Pages: 1 Open access contents