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Selective sweep for an enhancer involucrin allele identifies skin barrier adaptation out of Africa
Mary Elizabeth Mathyer, Erin A. Brettmann, Alina D. Schmidt, Zane A. Goodwin, Inez Y. Oh, Ashley M. Quiggle, Eric Tycksen, Natasha Ramakrishnan, Scot J. Matkovich, Emma Guttman-Yassky, John R. Edwards, Cristina de Guzman Strong
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Article Pages: 1 Open access contents
Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation
Eleonore Maury, Benoit Navez, Sonia M. Brichard
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Article Pages: 1 Open access contents
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease
Stephen Watt, Louella Vasquez, Klaudia Walter, Alice L. Mann, Kousik Kundu, Lu Chen, Ying Sims, Simone Ecker, Frances Burden, Samantha Farrow, Ben Farr, Valentina Iotchkova, Heather Elding, Daniel Mead, Manuel Tardaguila, Hannes Ponstingl, David Richardson, Avik Datta, Paul Flicek, Laura Clarke, Kate Downes, Tomi Pastinen, Peter Fraser, Mattia Frontini, Biola-Maria Javierre, Mikhail Spivakov, Nicole Soranzo
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Article Pages: 1 Open access contents
Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis
Michael F. Z. Wang, Madhav Mantri, Shao-Pei Chou, Gaetano J. Scuderi, David W. McKellar, Jonathan T. Butcher, Charles G. Danko, Iwijn De Vlaminck
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Article Pages: 1 Open access contents
Variable number tandem repeats mediate the expression of proximal genes
Mehrdad Bakhtiari, Jonghun Park, Yuan-Chun Ding, Sharona Shleizer-Burko, Susan L. Neuhausen, Bjarni V. Halldórsson, Kári Stefánsson, Melissa Gymrek, Vineet Bafna
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Article Pages: 1 Open access contents
FTO-mediated cytoplasmic m<sup>6</sup>A<sub>m</sub> demethylation adjusts stem-like properties in colorectal cancer cell
Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David
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Article Pages: 1 Open access contents
Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core
Haiyan Zhao, Natalie Young, Jens Kalchschmidt, Jenna Lieberman, Laila El Khattabi, Rafael Casellas, Francisco J. Asturias
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Article Pages: 1 Open access contents
The secreted endoribonuclease ENDU-2 from the soma protects germline immortality in <i>C. elegans</i>
Wenjing Qi, Erika D. V. Gromoff, Fan Xu, Qian Zhao, Wei Yang, Dietmar Pfeifer, Wolfgang Maier, Lijiang Long, Ralf Baumeister
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Article Pages: 1 Open access contents
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms
Jason R. Schwartz, Jing Ma, Jennifer Kamens, Tamara Westover, Michael P. Walsh, Samuel W. Brady, J. Robert Michael, Xiaolong Chen, Lindsey Montefiori, Guangchun Song, Gang Wu, Huiyun Wu, Cristyn Branstetter, Ryan Hiltenbrand, Michael F. Walsh, Kim E. Nichols, Jamie L. Maciaszek, Yanling Liu, Priyadarshini Kumar, John Easton, Scott Newman, Jeffrey E. Rubnitz, Charles G. Mullighan, Stanley Pounds, Jinghui Zhang, Tanja Gruber, Xiaotu Ma, Jeffery M. Klco
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Article Pages: 1 Open access contents
Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?
Ralf Baumeister, Coleen T. Murphy, Thomas Heimbucher
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Article Pages: 2 Open access contents