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Systematic inference and comparison of multi-scale chromatin sub-compartments connects spatial organization to cell phenotypes
Yuanlong Liu, Luca Nanni, Stephanie Sungalee, Marie Zufferey, Daniele Tavernari, Marco Mina, Stefano Ceri, Elisa Oricchio, Giovanni Ciriello
Publication Date: 10 May, 2021
Article Pages: 1 Open access contents
Interplay of two transcription factors for recruitment of the chromatin remodeling complex modulates fungal nitrosative stress response
Yunqing Jian, Zunyong Liu, Haixia Wang, Yun Chen, Yanni Yin, Youfu Zhao, Zhonghua Ma
Publication Date: 06 May, 2021
Article Pages: 1 Open access contents
Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo
Danielle R. Little, Anne M. Lynch, Yun Yan, Haruhiko Akiyama, Shioko Kimura, Jichao Chen
Publication Date: 04 May, 2021
Article Pages: 1 Open access contents
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
Yoshiharu Muto, Parker C. Wilson, Nicolas Ledru, Haojia Wu, Henrik Dimke, Sushrut S. Waikar, Benjamin D. Humphreys
Publication Date: 13 April, 2021
Article Pages: 1 Open access contents
Role of Hakai in m<sup>6</sup>A modification pathway in <i>Drosophila</i>
Yanhua Wang, Lifeng Zhang, Hang Ren, Lijuan Ma, Jian Guo, Decai Mao, Zhongwen Lu, Lijun Lu, Dong Yan
Publication Date: 12 April, 2021
Article Pages: 1 Open access contents
Epigenetic modulation of immune synaptic-cytoskeletal networks potentiates γδ T cell-mediated cytotoxicity in lung cancer
Rueyhung R. Weng, Hsuan-Hsuan Lu, Chien-Ting Lin, Chia-Chi Fan, Rong-Shan Lin, Tai-Chung Huang, Shu-Yung Lin, Yi-Jhen Huang, Yi-Hsiu Juan, Yi-Chieh Wu, Zheng-Ci Hung, Chi Liu, Xuan-Hui Lin, Wan-Chen Hsieh, Tzu-Yuan Chiu, Jung-Chi Liao, Yen-Ling Chiu, Shih-Yu Chen, Chong-Jen Yu, Hsing-Chen Tsai
Publication Date: 12 April, 2021
Article Pages: 1 Open access contents
Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism
Ruofan Yu, Xiaohua Cao, Luyang Sun, Jun-yi Zhu, Brian M Wasko, Wei Liu, Emeline Crutcher, Haiying Liu, Myeong Chan Jo, Lidong Qin, Matt Kaeberlein, Zhe Han, Weiwei Dang
Publication Date: 31 March, 2021
Article Pages: 1 Open access contents
Author Correction: An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine
Guang Song, Guohua Wang, Ximei Luo, Ying Cheng, Qifeng Song, Jun Wan, Cedric Moore, Hongjun Song, Peng Jin, Jiang Qian, Heng Zhu
Publication Date: 23 February, 2021
Article Pages: 1 Open access contents
Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention
Ian J. Groves, Sarah E. Jackson, Emma L. Poole, Aharon Nachshon, Batsheva Rozman, Michal Schwartz, Rab K. Prinjha, David F. Tough, John H. Sinclair, Mark R. Wills
Publication Date: 22 February, 2021
Article Pages: 1 Open access contents
Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation
Stephanie Dobersch, Karla Rubio, Indrabahadur Singh, Stefan Günther, Johannes Graumann, Julio Cordero, Rafael Castillo-Negrete, Minh Bao Huynh, Aditi Mehta, Peter Braubach, Hector Cabrera-Fuentes, Jürgen Bernhagen, Cho-Ming Chao, Saverio Bellusci, Andreas Günther, Klaus T. Preissner, Sita Kugel, Gergana Dobreva, Malgorzata Wygrecka, Thomas Braun, Dulce Papy-Garcia, Guillermo Barreto
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
Targeting NSD2-mediated SRC-3 liquid–liquid phase separation sensitizes bortezomib treatment in multiple myeloma
Jing Liu, Ying Xie, Jing Guo, Xin Li, Jingjing Wang, Hongmei Jiang, Ziyi Peng, Jingya Wang, Sheng Wang, Qian Li, Linquan Ye, Yuping Zhong, Qiguo Zhang, Xiaozhi Liu, David M. Lonard, Jin Wang, Bert W. O’Malley, Zhiqiang Liu
Publication Date: 15 February, 2021
Article Pages: 1 Open access contents
Chromosomal coordination and differential structure of asynchronous replicating regions
Britny Blumenfeld, Hagit Masika, Marganit Farago, Yishai Yehuda, Lamia Halaseh, Oriya Vardi, Rachel Rapoport, Rena Levin-Klein, Howard Cedar, Yehudit Bergman, Itamar Simon
Publication Date: 15 February, 2021
Article Pages: 1 Open access contents
CTCF loss has limited effects on global genome architecture in <i>Drosophila</i> despite critical regulatory functions
Anjali Kaushal, Giriram Mohana, Julien Dorier, Isa Özdemir, Arina Omer, Pascal Cousin, Anastasiia Semenova, Michael Taschner, Oleksandr Dergai, Flavia Marzetta, Christian Iseli, Yossi Eliaz, David Weisz, Muhammad Saad Shamim, Nicolas Guex, Erez Lieberman Aiden, Maria Cristina Gambetta
Publication Date: 12 February, 2021
Article Pages: 1 Open access contents
PRMT5 inhibition disrupts splicing and stemness in glioblastoma
Patty Sachamitr, Jolene C. Ho, Felipe E. Ciamponi, Wail Ba-Alawi, Fiona J. Coutinho, Paul Guilhamon, Michelle M. Kushida, Florence M. G. Cavalli, Lilian Lee, Naghmeh Rastegar, Victoria Vu, María Sánchez-Osuna, Jasmin Coulombe-Huntington, Evgeny Kanshin, Heather Whetstone, Mathieu Durand, Philippe Thibault, Kirsten Hart, Maria Mangos, Joseph Veyhl, Wenjun Chen, Nhat Tran, Bang-Chi Duong, Ahmed M. Aman, Xinghui Che, Xiaoyang Lan, Owen Whitley, Olga Zaslaver, Dalia Barsyte-Lovejoy, Laura M. Richards, Ian Restall, Amy Caudy, Hannes L. Röst, Zahid Quyoom Bonday, Mark Bernstein, Sunit Das, Michael D. Cusimano, Julian Spears, Gary D. Bader, Trevor J. Pugh, Mike Tyers, Mathieu Lupien, Benjamin Haibe-Kains, H. Artee Luchman, Samuel Weiss, Katlin B. Massirer, Panagiotis Prinos, Cheryl H. Arrowsmith, Peter B. Dirks
Publication Date: 12 February, 2021
Article Pages: 1 Open access contents
Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation
Yongming Du, Yinxia Yan, Si Xie, Hao Huang, Xin Wang, Ray Kit Ng, Ming-Ming Zhou, Chengmin Qian
Publication Date: 11 February, 2021
Article Pages: 1 Open access contents
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