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NUPR1 is a critical repressor of ferroptosis
Jiao Liu, Xinxin Song, Feimei Kuang, Qiuhong Zhang, Yangchun Xie, Rui Kang, Guido Kroemer, Daolin Tang
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Article Pages: 1 Open access contents
Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific <i>Pdcd10</i>-deficient mouse model
Huanjiao Jenny Zhou, Lingfeng Qin, Quan Jiang, Katie N. Murray, Haifeng Zhang, Busu Li, Qun Lin, Morven Graham, Xinran Liu, Jaime Grutzendler, Wang Min
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Article Pages: 1 Open access contents
Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
Xiongwen Cao, Alexandra Khitun, Yang Luo, Zhenkun Na, Thitima Phoodokmai, Khomkrit Sappakhaw, Elizabeth Olatunji, Chayasith Uttamapinant, Sarah A. Slavoff
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Article Pages: 1 Open access contents
Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins
David E. Place, R. K. Subbarao Malireddi, Jieun Kim, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti
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Article Pages: 1 Open access contents
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response
Wenjun Wang, Jianshuang Li, Junyang Tan, Miaomiao Wang, Jing Yang, Zhi-Min Zhang, Chuanzhou Li, Alexei G. Basnakian, Hong-Wen Tang, Norbert Perrimon, Qinghua Zhou
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Article Pages: 1 Open access contents
Mechanisms of muscle atrophy and hypertrophy: implications in health and disease
Roberta Sartori, Vanina Romanello, Marco Sandri
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Article Pages: 1 Open access contents
Structural insights into TSC complex assembly and GAP activity on Rheb
Huirong Yang, Zishuo Yu, Xizi Chen, Jiabei Li, Ningning Li, Jiaxuan Cheng, Ning Gao, Hai-Xin Yuan, Dan Ye, Kun-Liang Guan, Yanhui Xu
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Article Pages: 1 Open access contents
Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis
Zhengzheng Yan, Haihua Luo, Bingyao Xie, Tian Tian, Shan Li, Zhixia Chen, Jinghua Liu, Xuwen Zhao, Liyong Zhang, Yongqiang Deng, Timothy R. Billiar, Yong Jiang
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Article Pages: 1 Open access contents
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
Yawei Wang, Binlin Tang, Lei Long, Peng Luo, Wei Xiang, Xueru Li, Huilan Wang, Qingzhi Jiang, Xu Tan, Shenglin Luo, Huijuan Li, Ziwen Wang, Zelin Chen, Yu Leng, Zhongyong Jiang, Yang Wang, Le Ma, Rui Wang, Chunyu Zeng, Zujuan Liu, Yu Wang, Hongming Miao, Chunmeng Shi
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Article Pages: 1 Open access contents
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness
Johanna Grinat, Julian Heuberger, Ramon Oliveira Vidal, Neha Goveas, Frauke Kosel, Antoni Berenguer-Llergo, Andrea Kranz, Annika Wulf-Goldenberg, Diana Behrens, Bálint Melcher, Sascha Sauer, Michael Vieth, Eduard Batlle, A. Francis Stewart, Walter Birchmeier
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Article Pages: 1 Open access contents