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IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered <i>Salmonella</i>
Qiubin Lin, Li Rong, Xian Jia, Renhao Li, Bin Yu, Jingchu Hu, Xiao Luo, S. R. Badea, Chen Xu, Guofeng Fu, Kejiong Lai, Ming-chun Lee, Baozhong Zhang, Huarui Gong, Nan Zhou, Xiao Lei Chen, Shu-hai Lin, Guo Fu, Jian-Dong Huang
Publication Date: 05 May, 2021
Article Pages: 1 Open access contents
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions
Giuseppe Ercolano, Alejandra Gomez-Cadena, Nina Dumauthioz, Giulia Vanoni, Mario Kreutzfeldt, Tania Wyss, Liliane Michalik, Romain Loyon, Angela Ianaro, Ping-Chih Ho, Christophe Borg, Manfred Kopf, Doron Merkler, Philippe Krebs, Pedro Romero, Sara Trabanelli, Camilla Jandus
Publication Date: 05 May, 2021
Article Pages: 1 Open access contents
Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy
Jing Liu, Zhihao Zhao, Nasha Qiu, Quan Zhou, Guowei Wang, Haiping Jiang, Ying Piao, Zhuxian Zhou, Jianbin Tang, Youqing Shen
Publication Date: 23 April, 2021
Article Pages: 1 Open access contents
Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation
Enrique J. Arenas, Alex Martínez-Sabadell, Irene Rius Ruiz, Macarena Román Alonso, Marta Escorihuela, Antonio Luque, Carlos Alberto Fajardo, Alena Gros, Christian Klein, Joaquín Arribas
Publication Date: 23 February, 2021
Article Pages: 1 Open access contents
A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy
Junrong Li, Alain Wuethrich, Abu A. I. Sina, Han-Hao Cheng, Yuling Wang, Andreas Behren, Paul N. Mainwaring, Matt Trau
Publication Date: 17 February, 2021
Article Pages: 1 Open access contents
Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells
Rebekka Duhen, Carmen Ballesteros-Merino, Alexandra K. Frye, Eric Tran, Venkatesh Rajamanickam, Shu-Ching Chang, Yoshinobu Koguchi, Carlo B. Bifulco, Brady Bernard, Rom S. Leidner, Brendan D. Curti, Bernard A. Fox, Walter J. Urba, R. Bryan Bell, Andrew D. Weinberg
Publication Date: 16 February, 2021
Article Pages: 1 Open access contents
CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy
Alba Rodriguez-Garcia, Rachel C. Lynn, Mathilde Poussin, Monika A. Eiva, Lauren C. Shaw, Roddy S. O’Connor, Nicholas G. Minutolo, Victoria Casado-Medrano, Gonzalo Lopez, Takami Matsuyama, Daniel J. Powell
Publication Date: 09 February, 2021
Article Pages: 1 Open access contents
Single-cell profiling identifies pre-existing CD19-negative subclones in a B-ALL patient with CD19-negative relapse after CAR-T therapy
Tracy Rabilloud, Delphine Potier, Saran Pankaew, Mathis Nozais, Marie Loosveld, Dominique Payet-Bornet
Publication Date: 08 February, 2021
Article Pages: 1 Open access contents
Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma
Mehmet Kemal Samur, Mariateresa Fulciniti, Anil Aktas Samur, Abdul Hamid Bazarbachi, Yu-Tzu Tai, Rao Prabhala, Alejandro Alonso, Adam S. Sperling, Timothy Campbell, Fabio Petrocca, Kristen Hege, Shari Kaiser, Hervé Avet Loiseau, Kenneth C. Anderson, Nikhil C. Munshi
Publication Date: 08 February, 2021
Article Pages: 1 Open access contents
Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets
Trixy Fang, Jonatan Alvelid, Joel Spratt, Elena Ambrosetti, Ilaria Testa, Ana I. Teixeira
Publication Date: 08 February, 2021
Article Pages: 11 Open access contents