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Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
Roberta Peruzzo, Samantha Corrà, Roberto Costa, Michele Brischigliaro, Tatiana Varanita, Lucia Biasutto, Chiara Rampazzo, Daniele Ghezzi, Luigi Leanza, Mario Zoratti, Massimo Zeviani, Cristiano De Pittà, Carlo Viscomi, Rodolfo Costa, Ildikò Szabò
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Article Pages: 1 Open access contents
A modular tool to query and inducibly disrupt biomolecular condensates
Carmen N. Hernández-Candia, Sarah Pearce, Chandra L. Tucker
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Article Pages: 1 Open access contents
Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation
Sébastien Coassolo, Guillaume Davidson, Luc Negroni, Giovanni Gambi, Sylvain Daujat, Christophe Romier, Irwin Davidson
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Article Pages: 1 Open access contents
Asymmetric opening of the homopentameric 5-HT<sub>3A</sub> serotonin receptor in lipid bilayers
Yingyi Zhang, Patricia M. Dijkman, Rongfeng Zou, Martina Zandl-Lang, Ricardo M. Sanchez, Luise Eckhardt-Strelau, Harald Köfeler, Horst Vogel, Shuguang Yuan, Mikhail Kudryashev
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Article Pages: 1 Open access contents
<i>C. elegans</i> germ granules require both assembly and localized regulators for mRNA repression
Scott Takeo Aoki, Tina R. Lynch, Sarah L. Crittenden, Craig A. Bingman, Marvin Wickens, Judith Kimble
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Article Pages: 1 Open access contents
Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel
William R. Arnold, Lauren N. Carnevale, Zili Xie, Javier L. Baylon, Emad Tajkhorshid, Hongzhen Hu, Aditi Das
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Article Pages: 1 Open access contents
Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact
Sarah B. Nyenhuis, Nakul Karandikar, Volker Kiessling, Alex J. B. Kreutzberger, Anusa Thapa, Binyong Liang, Lukas K. Tamm, David S. Cafiso
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Article Pages: 1 Open access contents
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics
Monica C. Pillon, Meredith N. Frazier, Lucas B. Dillard, Jason G. Williams, Seda Kocaman, Juno M. Krahn, Lalith Perera, Cassandra K. Hayne, Jacob Gordon, Zachary D. Stewart, Mack Sobhany, Leesa J. Deterding, Allen L. Hsu, Venkata P. Dandey, Mario J. Borgnia, Robin E. Stanley
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Article Pages: 1 Open access contents
Accurate protein structure prediction with hydroxyl radical protein footprinting data
Sarah E. Biehn, Steffen Lindert
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Article Pages: 1 Open access contents
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir
Goran Kokic, Hauke S. Hillen, Dimitry Tegunov, Christian Dienemann, Florian Seitz, Jana Schmitzova, Lucas Farnung, Aaron Siewert, Claudia Höbartner, Patrick Cramer
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Article Pages: 1 Open access contents