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SOX-5 activates a novel RORγt enhancer to facilitate experimental autoimmune encephalomyelitis by promoting Th17 cell differentiation
Yi Tian, Chao Han, Zhiyuan Wei, Hui Dong, Xiaohe Shen, Yiqiang Cui, Xiaolan Fu, Zhiqiang Tian, Shufeng Wang, Jian Zhou, Di Yang, Yi Sun, Jizhao Yuan, Bing Ni, Yuzhang Wu
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Article Pages: 1 Open access contents
Granzyme B inhibition reduces disease severity in autoimmune blistering diseases
Sho Hiroyasu, Matthew R. Zeglinski, Hongyan Zhao, Megan A. Pawluk, Christopher T. Turner, Anika Kasprick, Chiharu Tateishi, Wataru Nishie, Angela Burleigh, Peter A. Lennox, Nancy Van Laeken, Nick J. Carr, Frank Petersen, Richard I. Crawford, Hiroshi Shimizu, Daisuke Tsuruta, Ralf J. Ludwig, David J. Granville
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Article Pages: 1 Open access contents
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression
Guojun Hou, Isaac T. W. Harley, Xiaoming Lu, Tian Zhou, Ning Xu, Chao Yao, Yuting Qin, Ye Ouyang, Jianyang Ma, Xinyi Zhu, Xiang Yu, Hong Xu, Dai Dai, Huihua Ding, Zhihua Yin, Zhizhong Ye, Jun Deng, Mi Zhou, Yuanjia Tang, Bahram Namjou, Ya Guo, Matthew T. Weirauch, Leah C. Kottyan, John B. Harley, Nan Shen
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Article Pages: 1 Open access contents
TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens
Rikio Yabe, Soo-Hyun Chung, Masanori A. Murayama, Sachiko Kubo, Kenji Shimizu, Yukiko Akahori, Takumi Maruhashi, Akimasa Seno, Tomonori Kaifu, Shinobu Saijo, Yoichiro Iwakura
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Article Pages: 1 Open access contents
Genetic and pharmacological inhibition of the nuclear receptor RORα regulates T<sub>H</sub>17 driven inflammatory disorders
Ran Wang, Sean Campbell, Mohammed Amir, Sarah A. Mosure, Molly A. Bassette, Amber Eliason, Mark S. Sundrud, Theodore M. Kamenecka, Laura A. Solt
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Article Pages: 1 Open access contents
Early-life-trauma triggers interferon-β resistance and neurodegeneration in a multiple sclerosis model via downregulated β1-adrenergic signaling
Yee Ming Khaw, Danish Majid, Sungjong Oh, Eunjoo Kang, Makoto Inoue
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Article Pages: 1 Open access contents
A Truncated Singleton NLR Causes Hybrid Necrosis in <i>Arabidopsis thaliana</i>
Ana Cristina Barragan, Maximilian Collenberg, Jinge Wang, Rachelle R Q Lee, Wei Yuan Cher, Fernando A Rabanal, Haim Ashkenazy, Detlef Weigel, Eunyoung Chae
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Article Pages: 17 Open access contents