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Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs
Henry Gerdes, Pedro Casado, Arran Dokal, Maruan Hijazi, Nosheen Akhtar, Ruth Osuntola, Vinothini Rajeeve, Jude Fitzgibbon, Jon Travers, David Britton, Shirin Khorsandi, Pedro R. Cutillas
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Article Pages: 1 Open access contents
Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
Álvaro Rol, Toni Todorovski, Pau Martin-Malpartida, Anna Escolà, Elena Gonzalez-Rey, Eric Aragón, Xavier Verdaguer, Mariona Vallès-Miret, Josep Farrera-Sinfreu, Eduard Puig, Jimena Fernández-Carneado, Berta Ponsati, Mario Delgado, Antoni Riera, Maria J. Macias
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Article Pages: 1 Open access contents
Embedding atomic cobalt into graphene lattices to activate room-temperature ferromagnetism
Wei Hu, Chao Wang, Hao Tan, Hengli Duan, Guinan Li, Na Li, Qianqian Ji, Ying Lu, Yao Wang, Zhihu Sun, Fengchun Hu, Wensheng Yan
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Article Pages: 1 Open access contents
Natural product fragment combination to performance-diverse pseudo-natural products
Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J. Foley, Rebecca Scheel, Carsten Strohmann, Andrey P. Antonchick, Herbert Waldmann
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Article Pages: 1 Open access contents
Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues
K. Venkatesan Iyer, Anna Taubenberger, Salma Ahmed Zeidan, Natalie A. Dye, Suzanne Eaton, Frank Jülicher
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Article Pages: 1 Open access contents
Cross-kingdom metabolic manipulation promotes <i>Salmonella</i> replication inside macrophages
Deyanira Pérez-Morales, Víctor H. Bustamante
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Article Pages: 1 Open access contents
Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity
Tushar Modi, Valeria A. Risso, Sergio Martinez-Rodriguez, Jose A. Gavira, Mubark D. Mebrat, Wade D. Van Horn, Jose M. Sanchez-Ruiz, S. Banu Ozkan
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Article Pages: 1 Open access contents
Electrocatalytic synthesis of heterocycles from biomass-derived furfuryl alcohols
Xuan Liu, Bo Li, Guanqun Han, Xingwu Liu, Zhi Cao, De-en Jiang, Yujie Sun
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Article Pages: 1 Open access contents
Single-molecule optical mapping of the distribution of DNA phosphorothioate epigenetics
Yue Wei, Qinqin Huang, Xihao Tian, Mingmin Zhang, Junkai He, Xingxiang Chen, Chao Chen, Zixin Deng, Zhiqiang Li, Shi Chen, Lianrong Wang
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Article Pages: 8 Open access contents
Ethidium bromide interactions with DNA: an exploration of a classic DNA–ligand complex with unbiased molecular dynamics simulations
Rodrigo Galindo-Murillo, Thomas E Cheatham
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Article Pages: 12 Open access contents