PLoS Genetics

ISSN: 1553-7390 (Print)

ISSN: 1553-7404 (Online)

Volume
Issue
 
CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury
Marcus Keatinge, Themistoklis M. Tsarouchas, Tahimina Munir, Nicola J. Porter, Juan Larraz, Davide Gianni, Hui-Hsin Tsai, Catherina G. Becker, David A. Lyons, Thomas Becker
Publication Date:
Research Article Pages: 1 Open access
The genomics of rapid climatic adaptation and parallel evolution in North American house mice
Kathleen G. Ferris, Andreas S. Chavez, Taichi A. Suzuki, Elizabeth J. Beckman, Megan Phifer-Rixey, Ke Bi, Michael W. Nachman
Publication Date:
Research Article Pages: 1 Open access
Mapping the degradation pathway of a disease-linked aspartoacylase variant
Sarah K. Gersing, Yong Wang, Martin Grønbæk-Thygesen, Caroline Kampmeyer, Lene Clausen, Martin Willemoës, Claes Andréasson, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Publication Date:
Research Article Pages: 1 Open access
Control of pre-replicative complex during the division cycle in <i>Chlamydomonas reinhardtii</i>
Amy E. Ikui, Noriko Ueki, Kresti Pecani, Frederick R. Cross
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Research Article Pages: 1 Open access
Subunit P60 of phosphatidylinositol 3-kinase promotes cell proliferation or apoptosis depending on its phosphorylation status
Yu-Qin Di, Yu-Meng Zhao, Ke-Yan Jin, Xiao-Fan Zhao
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Research Article Pages: 1 Open access
Toxic Y chromosome: Increased repeat expression and age-associated heterochromatin loss in male Drosophila with a young Y chromosome
Alison H. Nguyen, Doris Bachtrog
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Research Article Pages: 1 Open access
Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition
Sofie V. Nielsen, Rasmus Hartmann-Petersen, Amelie Stein, Kresten Lindorff-Larsen
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Research Article Pages: 1 Open access
Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers
Findley R. Finseth, Thomas C. Nelson, Lila Fishman
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Research Article Pages: 1 Open access
Putting the brakes on centromere drive in <i>Mimulus</i>
Ching-Ho Chang, Harmit S. Malik
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Discussion Pages: 1 Open access
A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment
Thomas K. Pak, Calvin S. Carter, Qihong Zhang, Sunny C. Huang, Charles Searby, Ying Hsu, Rebecca J. Taugher, Tim Vogel, Christopher C. Cychosz, Rachel Genova, Nina N. Moreira, Hanna Stevens, John A. Wemmie, Andrew A. Pieper, Kai Wang, Val C. Sheffield
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Research Article Pages: 1 Open access
A structural signature motif enlightens the origin and diversification of nuclear receptors
Brice Beinsteiner, Gabriel V. Markov, Stéphane Erb, Yassmine Chebaro, Alastair G. McEwen, Sarah Cianférani, Vincent Laudet, Dino Moras, Isabelle M. L. Billas
Publication Date:
Research Article Pages: 1 Open access
Transcriptome-wide investigation of stop codon readthrough in <i>Saccharomyces cerevisiae</i>
Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard Baker, Allan Jacobson
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Research Article Pages: 1 Open access
Evolutionary dynamics of the human pseudoautosomal regions
Bruno Monteiro, Miguel Arenas, Maria João Prata, António Amorim
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Research Article Pages: 1 Open access
MRLocus: Identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity
Anqi Zhu, Nana Matoba, Emma P. Wilson, Amanda L. Tapia, Yun Li, Joseph G. Ibrahim, Jason L. Stein, Michael I. Love
Publication Date:
Research Article Pages: 1 Open access
Trehalose and α-glucan mediate distinct abiotic stress responses in <i>Pseudomonas aeruginosa</i>
Stuart D. Woodcock, Karl Syson, Richard H. Little, Danny Ward, Despoina Sifouna, James K. M. Brown, Stephen Bornemann, Jacob G. Malone
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Research Article Pages: 1 Open access
The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis
Virginia L. King, Nathan K. Leclair, Alyssa M. Coulter, Kenneth G. Campellone
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Research Article Pages: 1 Open access
Tempo and mode in karyotype evolution revealed by a probabilistic model incorporating both chromosome number and morphology
Kohta Yoshida, Jun Kitano
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Research Article Pages: 1 Open access
Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease
Alvaro Ingles-Prieto, Nikolas Furthmann, Samuel H. Crossman, Alexandra-Madelaine Tichy, Nina Hoyer, Meike Petersen, Vanessa Zheden, Julia Biebl, Eva Reichhart, Attila Gyoergy, Daria E. Siekhaus, Peter Soba, Konstanze F. Winklhofer, Harald Janovjak
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Research Article Pages: 1 Open access
Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination
Sarah L. Whiteley, Clare E. Holleley, Susan Wagner, James Blackburn, Ira W. Deveson, Jennifer A. Marshall Graves, Arthur Georges
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Research Article Pages: 1 Open access
Aicardi-Goutières syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription–replication conflict regions
Kiwon Park, Jeongmin Ryoo, Heena Jeong, Minsu Kim, Sungwon Lee, Sung-Yeon Hwang, Jiyoung Ahn, Doyeon Kim, Hyungseok C. Moon, Daehyun Baek, Kwangsoo Kim, Hye Yoon Park, Kwangseog Ahn
Publication Date:
Research Article Pages: 1 Open access