Nucleic Acids Research
Home Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNA
Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNA
Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNA

The authors wish it to be known that, in their opinion, the first three authors should be regarded as joint First Authors.

Article Type: expression-of-concern Article History
Table of Contents
Jin,Sun,Zhao,Zheng,Zhang,Cai,He,Taira,Zhang,and Zhou: Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNA

Nucleic Acids Research, Volume 40, Issue 4, 1 February 2012, Pages 1797–1806, https://doi.org/10.1093/nar/gkr927

The Editors have been alerted by a reader that the two leftmost panels of Figure 5A in the above article are an exact replication (without citation or acknowledgement) from Figure 4A of (1). The authors have confirmed that the images are indeed identical and were intentionally duplicated to indicate that the NAR article is a follow-up study of the RNA article. The RNA article is cited several times as reference 8 in the NAR article but the authors have not disclosed that the images were reproduced from a previous publication in the figure caption.

While these irregularities may not fundamentally affect the results and conclusions of the article, the Editors nonetheless note that such duplication of data and figures without citation, acknowledgement and permission from the original publisher is unacceptable. Readers are advised to examine the details of this study with particular care.

REFERENCE

1. 

Zhou D. , ZhangJ., WangC., BliesathJ.R., HeQ., YuD., Li-HeZ., Wong-StaalF. A method for detecting and preventing negative RNA interference in preparation of lentiviral vectors for siRNA delivery. RNA. 2009; 15:732740.